Known targets — ChEMBL curated mechanism
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The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.67 |
| ▸ | TSHR | P16473 | 3/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL697179 | 1.00 | ALDH1A1 (0.67) | ALDH1A1TSHRTDP1HSD17B10SMN1; SMN2 | |
| Alcohol SCHEMBL9275621 | 1.00 | ALDH1A1 (0.67) | ALDH1A1TSHRTDP1HSD17B10SMN1; SMN2 | |
| Alcohol SCHEMBL1931178 | 1.00 | ALDH1A1 (0.67) | ALDH1A1TSHRTDP1HSD17B10SMN1; SMN2 | |
| Alcohol SCHEMBL8027671 | 1.00 | ALDH1A1 (0.67) | ALDH1A1TSHRTDP1HSD17B10SMN1; SMN2 | |
| Alcohol SCHEMBL5556136 | 1.00 | ALDH1A1 (0.67) | ALDH1A1TSHRTDP1HSD17B10SMN1; SMN2 | |
| Alcohol SCHEMBL6554416 | 1.00 | ALDH1A1 (0.67) | ALDH1A1TSHRTDP1HSD17B10SMN1; SMN2 | |
| Alcohol SCHEMBL4458809 | 1.00 | ALDH1A1 (0.67) | ALDH1A1TSHRTDP1HSD17B10SMN1; SMN2 | |
| Alcohol SCHEMBL2652301 | 1.00 | ALDH1A1 (0.67) | ALDH1A1TSHRTDP1HSD17B10SMN1; SMN2 | |
| Alcohol SCHEMBL10709971 | 1.00 | ALDH1A1 (0.67) | ALDH1A1TSHRTDP1HSD17B10SMN1; SMN2 | |
| Alcohol SCHEMBL1836225 | 1.00 | ALDH1A1 (0.67) | ALDH1A1TSHRTDP1HSD17B10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1713771-B1 | PROCESS FOR THE PREPARATION OF A NEW CRYSTALLINE FORM OF PERINDOPRIL | LEK PHARMACEUTICALS (SI) | 2014-03-05 | — | — | EP | disclosed |
| EP-1713771-A1 | NEW CRYSTALLINE FORM OF PERINDOPRIL | LEK Pharmaceuticals D.D. (SI) | 2006-10-25 | — | — | EP | disclosed |
| WO-2005068425-A1 | NEW CRYSTALLINE FORM OF PERINDOPRIL | LEK PHARMACEUTICALS D.D. (SI) | 2005-07-28 | — | — | WO | disclosed |