SCHEMBL6028322

SCHEMBL6028322

CN1C(=O)NC(=O)C1c1ccc(Cl)c(Cl)c1

nearest known ligand 0.43

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 1/20 0.43
SLC6A2 P23975 14/20 0.43
SLC6A3 Q01959 14/20 0.43
SLC6A4 P31645 8/20 0.41
CYP2D6 P10635 5/20 0.41
KCNH2 Q12809 5/20 0.41
ABCC9 O60706 1/20 0.39
ABCC8 Q09428 1/20 0.39
KCNJ11 Q14654 1/20 0.39
KCNJ8 Q15842 1/20 0.39
NPSR1 Q6W5P4 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15846794 0.73 BRD4 (0.42)
SCHEMBL9869833 0.67 CACNA1F (0.42) SLC6A2SLC6A3SLC6A4CYP2D6KCNH2
SCHEMBL14264660 0.66 CYP19A1 (0.59) BACE1SLC6A2SLC6A3SLC6A4
SCHEMBL5580256 0.66 TDP1 (0.56) BACE1SLC6A2SLC6A3SLC6A4CYP2D6
SCHEMBL25327137 0.64 SLC6A2 (0.38) SLC6A2SLC6A3SLC6A4CYP2D6KCNH2
SCHEMBL4023245 0.63 SLC6A2 (0.43) SLC6A2SLC6A3SLC6A4NPSR1
SCHEMBL11404396 0.62 SLC40A1 (0.36) SLC6A2SLC6A3SLC6A4ABCC9ABCC8
Dichlormezanone SCHEMBL29854540 0.62 LMNA (0.72) BACE1SLC6A2SLC6A3SLC6A4CYP2D6
Dichlormezanone SCHEMBL2107746 0.62 LMNA (0.72) BACE1SLC6A2SLC6A3SLC6A4CYP2D6
SCHEMBL8437322 0.61 NPSR1 (0.49) SLC6A2SLC6A3SLC6A4NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025235664-A1 PURINE NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO EMORY UNIVERSITY (US) 2025-11-13 WO claimed
EP-1625214-A1 NEW ENTEROVIRUS, VACCINES, MEDICAMENTS AND DIAGNOSTIC KITS Amsterdam Institute of Viral Genomics B.V. (NL) 2006-02-15 EP claimed
WO-2004104189-A1 NEW ENTEROVIRUS, VACCINES, MEDICAMENTS AND DIAGNOSTIC KITS AMSTERDAM INSTITUTE OF VIRAL GENOMICS B.V. (NL) 2004-12-02 WO claimed
US-20260124226-A1 4'-HALOGEN CONTAINING NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO UNIV EMORY (US) 2026-05-07 US disclosed
EP-4705284-A1 4'-HALOGEN CONTAINING NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO Emory University (US) 2026-03-11 EP disclosed
WO-2024233354-A1 4'-HALOGEN CONTAINING NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO EMORY UNIVERSITY (US) 2024-11-14 WO disclosed
US-20060182762-A1 Enterovirus, vaccines, medicaments and diagnostic kits AMSTERDAM INSTITUTE OF VIRAL GENOMICS B.V. (NL) 2006-08-17 US disclosed
EP-1625214-A1 NEW ENTEROVIRUS, VACCINES, MEDICAMENTS AND DIAGNOSTIC KITS Amsterdam Institute of Viral Genomics B.V. (NL) 2006-02-15 EP disclosed
WO-2004104189-A1 NEW ENTEROVIRUS, VACCINES, MEDICAMENTS AND DIAGNOSTIC KITS AMSTERDAM INSTITUTE OF VIRAL GENOMICS B.V. (NL) 2004-12-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060182762-A1 Enterovirus, vaccines, medicaments and diagnostic kits CD99, CD63, FAM83B BACE1 4141/4885SLC6A2 4412/4885SLC6A3 4397/4885
US-20260124226-A1 4'-HALOGEN CONTAINING NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO NSUN2, SARS1, SNRPE BACE1 4573/4885SLC6A2 929/4885SLC6A3 709/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.