SCHEMBL11404396

SCHEMBL11404396

CN1C(=O)NC(=N)C1c1ccc(F)c(F)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC40A1 Q9NP59 1/20 0.36
SLC6A2 P23975 4/20 0.35
SLC6A3 Q01959 4/20 0.35
SLC6A4 P31645 3/20 0.35
ABCC9 O60706 2/20 0.35
ABCC8 Q09428 2/20 0.35
KCNJ11 Q14654 2/20 0.35
KCNJ8 Q15842 2/20 0.35
CHRNB2 P17787 1/20 0.35
ADRA2C P18825 1/20 0.35
CHRNB4 P30926 1/20 0.35
CHRNA3 P32297 1/20 0.35
CHRNA7 P36544 1/20 0.35
CHRNA4 P43681 1/20 0.35
TMEM97 Q5BJF2 1/20 0.35
P2RX7 Q99572 3/20 0.33
ADRA1D P25100 5/20 0.33
ADRA1A P35348 5/20 0.33
ADRA1B P35368 5/20 0.33
HTR7 P34969 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7660734 0.77 ADRA1D (0.42) ADRA1DADRA1AADRA1B
SCHEMBL7662607 0.74 ADRA1D (0.53) ADRA1DADRA1AADRA1B
SCHEMBL6958220 0.68 P2RX7 (0.40) SLC6A2SLC6A3SLC6A4P2RX7HTR7
SCHEMBL7660499 0.66 ADRA1D (0.43) ADRA1DADRA1AADRA1BHTR7
SCHEMBL7605066 0.66 BRD4 (0.41) SLC6A2SLC6A3SLC6A4P2RX7ADRA1D
SCHEMBL7664087 0.65 ADRA1A (0.53) ADRA1DADRA1AADRA1BHTR7
SCHEMBL7660010 0.65 ADRA1A (0.53) ADRA1DADRA1AADRA1BHTR7
SCHEMBL7658023 0.65 ADRA1A (0.53) ADRA1DADRA1AADRA1BHTR7
SCHEMBL10308940 0.64 MTOR (0.38) SLC6A2SLC6A3SLC6A4P2RX7
SCHEMBL8168600 0.64 MTOR (0.38) SLC6A2SLC6A3SLC6A4P2RX7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0024570-A1 5-Imino-imidazoline-2-ones, herbicides containing them and process for destructing undesired plants BASF Aktiengesellschaft (DE) 1981-03-11 EP disclosed