Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 4/20 | 0.34 |
| ▸ | HRH1 | P35367 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5570276 | 0.74 | — | — | |
| SCHEMBL5569277 | 0.67 | KMT2A (0.37) | KMT2A | |
| SCHEMBL3313116 | 0.64 | CTSK (0.44) | — | |
| SCHEMBL3307583 | 0.64 | CYP1A2 (0.39) | — | |
| SCHEMBL13396343 | 0.62 | CTSL (0.46) | KMT2A | |
| SCHEMBL14573973 | 0.61 | CTSK (0.39) | KMT2A | |
| SCHEMBL4433837 | 0.60 | ITGB3 (0.39) | — | |
| SCHEMBL3307162 | 0.60 | CYP1A2 (0.40) | — | |
| SCHEMBL3307159 | 0.60 | CYP1A2 (0.40) | — | |
| SCHEMBL13396534 | 0.60 | CTSK (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1626955-A1 | CAPTOPRIL DERIVATIVES | Nicox S.A. (FR) | 2006-02-22 | — | — | EP | disclosed |
| WO-2004106300-A1 | CAPTOPRIL DERIVATIVES | NICOX S.A. (FR) | 2004-12-09 | — | — | WO | disclosed |