Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.67 |
| ▸ | CA1 | P00915 | 2/20 | 0.67 |
| ▸ | CA3 | P07451 | 2/20 | 0.67 |
| ▸ | CA4 | P22748 | 2/20 | 0.67 |
| ▸ | CA5A | P35218 | 2/20 | 0.67 |
| ▸ | CA7 | P43166 | 2/20 | 0.67 |
| ▸ | CA9 | Q16790 | 2/20 | 0.67 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.67 |
| ▸ | CA2 | P00918 | 1/20 | 0.67 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.57 |
| ▸ | HPGD | P15428 | 6/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.57 |
| ▸ | LCK | P06239 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | STAT1 | P42224 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6031059 | 0.83 | CA12 (0.78) | CA12CA1CA3CA4CA5A | |
| SCHEMBL28878363 | 0.80 | CA12 (1.00) | CA12CA1CA3CA4CA5A | |
| SCHEMBL6030323 | 0.80 | CA12 (0.68) | CA12CA1CA3CA4CA5A | |
| SCHEMBL6030326 | 0.80 | CA12 (0.68) | CA12CA1CA3CA4CA5A | |
| SCHEMBL28546496 | 0.77 | CA12 (0.72) | CA12CA1CA3CA4CA5A | |
| SCHEMBL6030760 | 0.76 | ALDH1A1 (0.71) | CA12CA1CA3CA4CA5A | |
| SCHEMBL3911979 | 0.75 | KDM4E (0.69) | CA12CA1CA3CA4CA5A | |
| SCHEMBL14424527 | 0.75 | KDM4E (0.73) | CA12CA1CA3CA4CA5A | |
| SCHEMBL571861 | 0.74 | KDM4E (0.58) | CA12CA1CA3CA4CA5A | |
| SCHEMBL28895373 | 0.74 | KDM4E (0.62) | CA12CA1CA3CA4CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060105458-A1 | Caged tetracycline (derivatives), their generation, and their use for photoactivated gene expression | MAX-PLANCK-GESELLSCHAFT ZUR FODERUNG DER WISSENSCHAFTEN E.V. (DE) | 2006-05-18 | — | — | US | claimed |
| EP-1534839-A1 | CAGED TETRACYCLINE (DERIVATIVES), THEIR GENERATION, AND THEIR USE FOR PHOTOACTIVATED GENE EXPRESSION | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2005-06-01 | — | — | EP | claimed |
| WO-2004018686-A1 | CAGED TETRACYCLINE (DERIVATIVES), THEIR GENERATION, AND THEIR USE FOR PHOTOACTIVATED GENE EXPRESSION | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2004-03-04 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060105458-A1 | Caged tetracycline (derivatives), their generation, and their use for photoactivated gene expression | TET1, TEAD2, MYC | CA12 4516/4885CA1 4413/4885CA3 4568/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.