Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.71 |
| ▸ | HPGD | P15428 | 5/20 | 0.71 |
| ▸ | GAA | P10253 | 3/20 | 0.71 |
| ▸ | MAOB | P27338 | 3/20 | 0.71 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.62 |
| ▸ | GLA | P06280 | 3/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.62 |
| ▸ | RAB9A | P51151 | 3/20 | 0.60 |
| ▸ | NPC1 | O15118 | 3/20 | 0.60 |
| ▸ | CA12 | O43570 | 3/20 | 0.60 |
| ▸ | CA2 | P00918 | 3/20 | 0.60 |
| ▸ | CA9 | Q16790 | 3/20 | 0.60 |
| ▸ | CA3 | P07451 | 2/20 | 0.60 |
| ▸ | CA6 | P23280 | 2/20 | 0.60 |
| ▸ | CA7 | P43166 | 2/20 | 0.60 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | CA4 | P22748 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1104931 | 0.83 | ALDH1A1 (1.00) | ALDH1A1HPGDGAAMAOBSLC16A3 | |
| SCHEMBL52650 | 0.81 | ALDH1A1 (0.81) | ALDH1A1HPGDGAAMAOBSLC16A3 | |
| SCHEMBL1366230 | 0.81 | ALDH1A1 (0.81) | ALDH1A1HPGDGAAMAOBSLC16A3 | |
| SCHEMBL16227665 | 0.81 | ALDH1A1 (0.66) | ALDH1A1HPGDGAAMAOBSLC16A3 | |
| SCHEMBL203997 | 0.80 | SLC16A3 (1.00) | ALDH1A1HPGDGAAMAOBSLC16A3 | |
| SCHEMBL22001514 | 0.80 | ALDH1A1 (0.72) | ALDH1A1HPGDGAAMAOBSLC16A3 | |
| SCHEMBL6687148 | 0.79 | MAOB (0.76) | ALDH1A1HPGDGAAMAOBSLC16A3 | |
| SCHEMBL11829416 | 0.79 | ALDH1A1 (0.76) | ALDH1A1HPGDGAAMAOBSLC16A3 | |
| SCHEMBL455614 | 0.79 | ALDH1A1 (0.76) | ALDH1A1HPGDGAAMAOBSLC16A3 | |
| SCHEMBL22001389 | 0.78 | ALDH1A1 (0.70) | ALDH1A1HPGDGAAMAOBSLC16A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060105458-A1 | Caged tetracycline (derivatives), their generation, and their use for photoactivated gene expression | MAX-PLANCK-GESELLSCHAFT ZUR FODERUNG DER WISSENSCHAFTEN E.V. (DE) | 2006-05-18 | — | — | US | disclosed |
| EP-1534839-A1 | CAGED TETRACYCLINE (DERIVATIVES), THEIR GENERATION, AND THEIR USE FOR PHOTOACTIVATED GENE EXPRESSION | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2005-06-01 | — | — | EP | disclosed |
| WO-2004018686-A1 | CAGED TETRACYCLINE (DERIVATIVES), THEIR GENERATION, AND THEIR USE FOR PHOTOACTIVATED GENE EXPRESSION | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2004-03-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060105458-A1 | Caged tetracycline (derivatives), their generation, and their use for photoactivated gene expression | TET1, TEAD2, MYC | ALDH1A1 2886/4885HPGD 2174/4885GAA 2442/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.