Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 2/20 | 0.36 |
| ▸ | ITGA4 | P13612 | 5/20 | 0.35 |
| ▸ | ITGB7 | P26010 | 5/20 | 0.35 |
| ▸ | ITGB1 | P05556 | 4/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2469667 | 0.85 | SLC6A9 (0.38) | ITGA4ITGB7ITGB1SLC6A9MMP13 | |
| SCHEMBL2701371 | 0.83 | ITGA4 (0.35) | KCNA3ITGA4ITGB7ITGB1SLC6A9 | |
| SCHEMBL2471159 | 0.83 | SLC6A9 (0.36) | ITGA4ITGB7ITGB1MAPK1SLC6A9 | |
| SCHEMBL2496178 | 0.80 | SLC6A9 (0.41) | ITGA4ITGB7ITGB1SLC6A9MMP13 | |
| SCHEMBL2471820 | 0.79 | KCNA3 (0.44) | KCNA3HPGDSLC6A9MEN1KMT2A | |
| SCHEMBL2468487 | 0.79 | ALDH1A1 (0.33) | ITGA4ITGB7ITGB1SLC6A9ALDH1A1 | |
| SCHEMBL4403843 | 0.78 | ALDH1A1 (0.42) | KCNA3ITGA4ITGB7ITGB1HPGD | |
| SCHEMBL2469411 | 0.78 | SMN1; SMN2 (0.34) | ITGA4ITGB7ITGB1KMT2AALDH1A1 | |
| SCHEMBL2468906 | 0.77 | ITGA4 (0.34) | ITGA4ITGB7ITGB1SLC6A9MEN1 | |
| SCHEMBL2699894 | 0.77 | ALDH1A1 (0.44) | KCNA3ITGA4ITGB7ITGB1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7005436-B2 | Heterocyclo inhibitors of potassium channel function | BRISTOL MYERS SQUIBB COMPANY (US) | 2006-02-28 | — | — | US | disclosed |