Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RB1 | P06400 | 8/20 | 0.48 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | PER2 | O15055 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6033064 | 0.80 | RB1 (0.50) | RB1SLC2A1MEN1ALDH1A1HPGD | |
| SCHEMBL6031429 | 0.76 | HTR6 (0.48) | RB1SLC2A1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL6031575 | 0.74 | RB1 (0.45) | RB1SLC2A1MEN1HPGDKMT2A | |
| SCHEMBL19161100 | 0.70 | MCHR1 (0.41) | MEN1ALDH1A1HPGDKMT2AHSD17B10 | |
| SCHEMBL4041356 | 0.67 | HSD17B10 (0.43) | MEN1ALDH1A1HPGDKMT2AHSD17B10 | |
| SCHEMBL6824387 | 0.67 | CA1 (0.53) | MEN1ALDH1A1KMT2AHSD17B10BCHE | |
| SCHEMBL4196380 | 0.65 | RB1 (1.00) | RB1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL4369870 | 0.65 | CYP2D6 (0.47) | MEN1ALDH1A1HPGDKMT2AHSD17B10 | |
| Hydrochloric Acid SCHEMBL4162233 | 0.64 | RB1 (1.00) | RB1MEN1KMT2AGAA | |
| SCHEMBL14543932 | 0.64 | PDE1A (0.44) | MEN1ALDH1A1KMT2AHSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678137-A1 | COMPOSITIONS AND METHODS FOR VIRAL INHIBITION | CHIRON CORPORATION (US) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005037791-A1 | COMPOSITIONS AND METHODS FOR VIRAL INHIBITION | CHIRON CORPORATION (US) | 2005-04-28 | — | — | WO | disclosed |