Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 4/20 | 0.48 |
| ▸ | HRH2 | P25021 | 2/20 | 0.48 |
| ▸ | HRH1 | P35367 | 2/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6031575 | 0.83 | RB1 (0.45) | RB1SLC2A1CYP3A4HPGDTBXA2R | |
| SCHEMBL6029922 | 0.76 | RB1 (0.48) | RB1SLC2A1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL6033064 | 0.76 | RB1 (0.50) | RB1SLC2A1ALDH1A1HPGDMAPK1 | |
| SCHEMBL25818911 | 0.72 | HTR6 (0.85) | HTR6HRH2HRH1HRH3CHRM2 | |
| SCHEMBL11632574 | 0.69 | HTR6 (0.44) | HTR6HRH2HRH1HRH3CHRM2 | |
| SCHEMBL24110035 | 0.67 | HTR6 (0.53) | HTR6HRH2HRH1HRH3CHRM2 | |
| SCHEMBL11826363 | 0.66 | CYP2D6 (0.59) | HTR6HRH2HRH1HRH3CHRM2 | |
| SCHEMBL7412035 | 0.66 | HTR6 (0.55) | HTR6HRH2HRH1HRH3CHRM2 | |
| SCHEMBL24110458 | 0.66 | HTR6 (0.55) | HTR6HRH2HRH1HRH3CHRM2 | |
| SCHEMBL4041356 | 0.66 | HSD17B10 (0.43) | HTR2AHTR2CKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678137-A1 | COMPOSITIONS AND METHODS FOR VIRAL INHIBITION | CHIRON CORPORATION (US) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005037791-A1 | COMPOSITIONS AND METHODS FOR VIRAL INHIBITION | CHIRON CORPORATION (US) | 2005-04-28 | — | — | WO | disclosed |