Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RB1 | P06400 | 8/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 2/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.35 |
| ▸ | CDK4 | P11802 | 1/20 | 0.33 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6029922 | 0.80 | RB1 (0.48) | RB1BCHEACHEMEN1KMT2A | |
| SCHEMBL6031575 | 0.76 | RB1 (0.45) | RB1MEN1KMT2AHPGDSLC2A1 | |
| SCHEMBL6031429 | 0.76 | HTR6 (0.48) | RB1ALDH1A1HPGDHSD17B10MAPK1 | |
| SCHEMBL7427777 | 0.72 | CA1 (0.53) | MEN1KMT2AALDH1A1HSD17B10CRHBP | |
| SCHEMBL21448630 | 0.70 | MEN1 (0.53) | MEN1KMT2AALDH1A1CRHBPCRHR2 | |
| SCHEMBL21448631 | 0.70 | MEN1 (0.53) | MEN1KMT2AALDH1A1CRHBPCRHR2 | |
| SCHEMBL31469390 | 0.70 | MEN1 (0.53) | MEN1KMT2AALDH1A1CRHBPCRHR2 | |
| SCHEMBL21448628 | 0.70 | MEN1 (0.53) | MEN1KMT2AALDH1A1CRHBPCRHR2 | |
| SCHEMBL4728728 | 0.70 | MEN1 (0.53) | MEN1KMT2AALDH1A1CRHBPCRHR2 | |
| SCHEMBL31469424 | 0.68 | MEN1 (0.50) | MEN1KMT2AALDH1A1CRHBPCRHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678137-A1 | COMPOSITIONS AND METHODS FOR VIRAL INHIBITION | CHIRON CORPORATION (US) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005037791-A1 | COMPOSITIONS AND METHODS FOR VIRAL INHIBITION | CHIRON CORPORATION (US) | 2005-04-28 | — | — | WO | disclosed |