Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.46 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6030746 | 0.87 | CSNK2A2 (0.41) | CSNK2A2CSNK2A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6031351 | 0.85 | HSD17B10 (0.42) | CSNK2A2CSNK2A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6030754 | 0.84 | CSNK2A2 (0.48) | CSNK2A2CSNK2A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6031306 | 0.83 | HSD17B10 (0.54) | CSNK2A2CSNK2A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6031439 | 0.83 | HSD17B10 (0.54) | CSNK2A2CSNK2A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6029587 | 0.83 | HSD17B10 (0.54) | CSNK2A2CSNK2A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6030418 | 0.83 | HSD17B10 (0.54) | CSNK2A2CSNK2A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6031060 | 0.83 | HSD17B10 (0.54) | CSNK2A2CSNK2A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6031411 | 0.83 | HSD17B10 (0.54) | CSNK2A2CSNK2A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6031638 | 0.83 | HSD17B10 (0.54) | CSNK2A2CSNK2A1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7064122-B2 | Pancreatic lipase inhibitor compounds, their synthesis and use | OSI PHARMACEUTICALS, INC. (US) | 2006-06-20 | — | — | US | disclosed |
| EP-1467978-A4 | PANCREATIC LIPASE INHIBITOR COMPOUNDS, THEIR SYNTHESIS AND USE | OSI PHARM INC (US) | 2005-11-02 | — | — | EP | disclosed |
| EP-1467978-A1 | PANCREATIC LIPASE INHIBITOR COMPOUNDS, THEIR SYNTHESIS AND USE | OSI Pharmaceuticals, Inc. (US) | 2004-10-20 | — | — | EP | disclosed |
| US-20030195199-A1 | Pancreatic lipase inhibitor compounds, their synthesis and use | OSI PHARMACEUTICALS, INC. | 2003-10-16 | — | — | US | disclosed |
| WO-2003053944-A1 | PANCREATIC LIPASE INHIBITOR COMPOUNDS, THEIR SYNTHESIS AND USE | OSI PHARMACEUTICALS, INC. (US) | 2003-07-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030195199-A1 | Pancreatic lipase inhibitor compounds, their synthesis and use | PNLIP, LIPC, CEL | CSNK2A2 1345/4885CSNK2A1 1181/4885NPC1 175/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.