Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CFTR | P13569 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ANPEP | P15144 | 1/20 | 0.34 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.34 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7189196 | 0.92 | ALDH1A1 (0.55) | ALDH1A1CFTRLMNAPOLBKMT2A | |
| SCHEMBL7182278 | 0.84 | L3MBTL1 (0.41) | ALDH1A1CFTRLMNAPOLBKMT2A | |
| SCHEMBL6031070 | 0.84 | NPSR1 (0.43) | ALDH1A1CFTRLMNAPOLBKMT2A | |
| SCHEMBL28191979 | 0.83 | NPSR1 (0.42) | ALDH1A1CFTRLMNAKMT2AMEN1 | |
| SCHEMBL7177532 | 0.83 | ALDH1A1 (0.43) | ALDH1A1CFTRLMNAPOLBKMT2A | |
| SCHEMBL7181593 | 0.82 | ALDH1A1 (0.53) | ALDH1A1CFTRPOLBKMT2AMEN1 | |
| SCHEMBL7182680 | 0.82 | TSHR (0.41) | CFTRLMNAPOLBKMT2AMEN1 | |
| SCHEMBL1138267 | 0.81 | KMT2A (0.42) | ALDH1A1CFTRLMNAPOLBKMT2A | |
| SCHEMBL15637131 | 0.81 | CFTR (0.38) | ALDH1A1CFTRLMNAPOLBKMT2A | |
| SCHEMBL7180466 | 0.81 | CETP (0.43) | ALDH1A1CFTRLMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7109250-B2 | Multimer forms of acylphosphines and their derivatives | CIBA SPECIALTY CHEMICALS CORP. (US) | 2006-09-19 | — | — | US | disclosed |
| US-20050004247-A1 | Multimer forms of acylphosphines and their derivatives | CIBA SPECIALTY CHEMICALS CORP. | 2005-01-06 | — | — | US | disclosed |
| EP-1446410-A1 | MULTIMER FORMS OF ACYLPHOSPHINES AND THEIR DERIVATIVES | Ciba SC Holding AG (CH) | 2004-08-18 | — | — | EP | disclosed |
| WO-2003044030-A1 | MULTIMER FORMS OF ACYLPHOSPHINES AND THEIR DERIVATIVES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2003-05-30 | — | — | WO | disclosed |