Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ESRRB | O95718 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MIF | P14174 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11127938 | 0.88 | KMT2A (0.43) | KMT2ASMN1; SMN2AAK1CYP1A2CYP2D6 | |
| SCHEMBL11127941 | 0.88 | KMT2A (0.43) | KMT2ASMN1; SMN2AAK1CYP1A2CYP2D6 | |
| SCHEMBL11114111 | 0.88 | AAK1 (0.50) | KMT2ASMN1; SMN2AAK1CYP1A2CYP2D6 | |
| SCHEMBL8125424 | 0.81 | AAK1 (0.48) | KMT2ASMN1; SMN2AAK1CYP1A2CYP2D6 | |
| SCHEMBL8136302 | 0.81 | AAK1 (0.48) | KMT2ASMN1; SMN2AAK1CYP1A2CYP2D6 | |
| SCHEMBL3247050 | 0.76 | AAK1 (0.49) | KMT2ASMN1; SMN2AAK1MAPTPOLB | |
| SCHEMBL6031731 | 0.76 | KMT2A (0.43) | KMT2ASMN1; SMN2CYP1A2CYP2D6MAPT | |
| SCHEMBL25166096 | 0.75 | AAK1 (0.50) | KMT2AAAK1CYP1A2CYP2D6MAPT | |
| SCHEMBL11315574 | 0.74 | MEN1 (0.42) | KMT2ASMN1; SMN2AAK1MAPTPOLB | |
| SCHEMBL11112454 | 0.73 | AAK1 (0.46) | SMN1; SMN2AAK1CYP1A2CYP2D6HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060135790-A1 | Process for the preparation of an alpha-amino carbonyl compound | DSM IP ASSETS B.V. (NL) | 2006-06-22 | — | — | US | disclosed |
| EP-1599441-A1 | PROCESS FOR THE PREPARATION OF AN ALPHA-AMINO CARBONYL COMPOUND | DSM IP Assets B.V. (NL) | 2005-11-30 | — | — | EP | disclosed |
| WO-2004078702-A1 | PROCESS FOR THE PREPARATION OF AN α-AMINO CARBONYL COMPOUND | DSM IP ASSETS B.V. (NL) | 2004-09-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060135790-A1 | Process for the preparation of an alpha-amino carbonyl compound | PAM, GRHPR, DAO | KMT2A 1992/4885SMN1; SMN2 3583/4885AAK1 2912/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.