SCHEMBL6030679

SCHEMBL6030679

CC(N)c1ncc(Cl)cc1Cl

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.44
HTT P42858 2/20 0.44
TP53 P04637 1/20 0.44
CYP2C9 P11712 1/20 0.41
TSHR P16473 1/20 0.41
APEX1 P27695 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
PLAU P00749 1/20 0.40
MAPK1 P28482 1/20 0.36
S1PR1 P21453 2/20 0.36
S1PR3 Q99500 2/20 0.36
PDCD1 Q15116 2/20 0.36
CD274 Q9NZQ7 2/20 0.36
ADRB2 P07550 1/20 0.35
KMT2A Q03164 2/20 0.33
MEN1 O00255 1/20 0.33
HSD17B10 Q99714 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16043880 1.00 LMNA (0.44) LMNAHTTTP53CYP2C9TSHR
SCHEMBL16044116 1.00 LMNA (0.44) LMNAHTTTP53CYP2C9TSHR
SCHEMBL2609312 0.83 LMNA (0.44) LMNAHTTTP53CYP2C9TSHR
SCHEMBL18244479 0.81 LMNA (0.42) LMNAHTTCYP2C9TSHRAPEX1
SCHEMBL29441178 0.80 KMT2A (0.35) LMNAHTTTP53SMN1; SMN2MAPK1
SCHEMBL17823946 0.80 KMT2A (0.35) LMNAHTTTP53SMN1; SMN2MAPK1
SCHEMBL13119982 0.80 S1PR1 (0.47) LMNAHTTTP53PLAUS1PR1
SCHEMBL17823722 0.80 S1PR3 (0.42) S1PR1S1PR3
SCHEMBL21725703 0.80 S1PR3 (0.42) S1PR1S1PR3
SCHEMBL29441073 0.80 S1PR3 (0.42) S1PR1S1PR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4705294-A1 FUSED BICYCLIC HETEROCYCLYL COMPOUNDS AS CCR4 MODULATORS Aurigene Oncology Limited (IN) 2026-03-11 EP disclosed
WO-2024228132-A1 FUSED BICYCLIC HETEROCYCLYL COMPOUNDS AS CCR4 MODULATORS AURIGENE ONCOLOGY LIMITED (IN) 2024-11-07 WO disclosed
US-7074742-B2 Pyridinyl amides and imides for use as fungicides E. I. DU PONT DE NEMOURS AND COMPANY (US) 2006-07-11 US disclosed
US-20050020643-A1 Pyridinyl amides and compositions thereof for use as fungicides E.I. DU PONT DE NEMOURS AND COMPANY 2005-01-27 US disclosed
EP-1485355-A2 PYRIDINYL AMIDES AND COMPOSITIONS THEREOF FOR USE AS FUNGICIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 2004-12-15 EP disclosed
US-20040044040-A1 Pyridinyl amides and imides for use as fungicides E. I. DU PONT DE NEMOURS AND COMPANY 2004-03-04 US disclosed
WO-2003080576-A2 PYRIDINYL AMIDES AND COMPOSITIONS THEREOF FOR USE AS FUNGICIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 2003-10-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040044040-A1 Pyridinyl amides and imides for use as fungicides CBR1, CBR3, AOC3 LMNA 1500/4885HTT 4580/4885TP53 4794/4885
US-20050020643-A1 Pyridinyl amides and compositions thereof for use as fungicides ME3, CYC1, ME2 LMNA 2451/4885HTT 4182/4885TP53 3082/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.