SCHEMBL6030728

SCHEMBL6030728

CC=CN(C)c1ccc(O)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 2/20 0.47
HSD17B10 Q99714 5/20 0.39
ESR1 P03372 5/20 0.39
ALOX15 P16050 4/20 0.39
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
HIF1A Q16665 3/20 0.39
LMNA P02545 3/20 0.39
CYP3A4 P08684 3/20 0.39
MAPT P10636 2/20 0.39
NR3C1 P04150 1/20 0.39
TP53 P04637 1/20 0.39
CYP1A2 P05177 1/20 0.39
ADORA3 P0DMS8 1/20 0.39
GAA P10253 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C9 P11712 1/20 0.39
ALOX12 P18054 1/20 0.39
CYP2C19 P33261 1/20 0.39
OPRD1 P41143 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8559716 0.76 MEN1 (0.41) HSD17B10ALOX15MEN1KMT2ALMNA
SCHEMBL8559720 0.76 MEN1 (0.41) HSD17B10ALOX15MEN1KMT2ALMNA
SCHEMBL17436357 0.76 MEN1 (0.41) HSD17B10ALOX15MEN1KMT2ALMNA
SCHEMBL1031223 0.74 APP (0.48) APPHSD17B10ESR1ALOX15MEN1
SCHEMBL14390627 0.74 APP (0.48) APPHSD17B10ESR1ALOX15MEN1
SCHEMBL27529727 0.74 APP (0.53) APPHSD17B10ESR1MEN1KMT2A
Hydroquinone SCHEMBL27680182 0.71 CYP3A4 (0.61) APPHSD17B10ESR1ALOX15MEN1
4-Dimethylaminophenol SCHEMBL9792507 0.69 APP (0.73) APPHSD17B10ALOX15MEN1KMT2A
4-Dimethylaminophenol SCHEMBL224308 0.69 APP (0.73) APPHSD17B10ALOX15MEN1KMT2A
SCHEMBL926427 0.69 APP (0.52) APPHSD17B10ESR1ALOX15MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022191865-A1 HAIR COLORANT ASSESSMENT, SELECTION AND FORMULATION SYSTEM Innovative Beauty LLC (US) 2022-09-15 WO disclosed
US-20220283032-A1 Hair Colorant Assessment, Selection And Formulation System Innovative Beauty LLC (US) 2022-09-08 US disclosed
US-11378457-B1 Hair colorant assessment, selection and formulation system Innovative Beauty LLC (US) 2022-07-05 US disclosed
US-11137291-B1 Hair colorant assessment, selection and formulation system Innovative Beauty LLC (US) 2021-10-05 US disclosed
US-6986886-B2 Hair conditioning compositions and their use in hair coloring compositions THE PROCTER & GAMBLE COMPANY (US) 2006-01-17 US disclosed
US-20040158941-A1 Hair colouring and conditioning compositions THE PROCTER & GAMBLE COMPANY (US) 2004-08-19 US disclosed
US-20040158938-A1 Method for colouring hair THE PROCTER & GAMBLE COMPANY 2004-08-19 US disclosed
US-6758866-B2 AQUEOUS SOLUTION OF CHELATE COMPOUND, OXIDATION COLOR DYE AND COUPLER UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2004-07-06 US disclosed
US-6695888-B2 COMPLEX TRANSITION METAL HAIR DYE UNILEVER HOME & PERSONAL CARE, USA, DIVISION OF CONOPCO, INC. 2004-02-24 US disclosed
WO-2004014328-A1 ONE STEP HAIR COLORING COMPOSITIONS COMPRISING WATER SOLUBLE CARBONATE RELEASING SALTS UNILEVER PLC (GB) 2004-02-19 WO disclosed
EP-0869769-A1 HAIR BLEACHING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1998-10-14 EP disclosed
WO-1998027943-A1 HAIR COLORING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1998-07-02 WO disclosed
WO-1998027941-A1 HAIR COLORING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1998-07-02 WO disclosed
WO-1998027942-A1 HAIR COLORING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1998-07-02 WO disclosed
WO-1998027945-A1 HAIR COLORING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1998-07-02 WO disclosed
WO-1998027944-A1 HAIR COLORING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1998-07-02 WO disclosed
WO-1997024106-A1 HAIR COLORING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1997-07-10 WO disclosed
WO-1997024105-A1 HAIR COLORING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1997-07-10 WO disclosed
WO-1997024108-A1 HAIR BLEACHING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1997-07-10 WO disclosed
US-3957424-A Enzyme-activated oxidative process for coloring hair THE PROCTER & GAMBLE COMPANY (US) 1976-05-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040158941-A1 Hair colouring and conditioning compositions FNIP1, CUTA, SHH APP 3486/4885HSD17B10 426/4885ESR1 4477/4885
US-20040158938-A1 Method for colouring hair COX5B, SHH, DNMT3A APP 1156/4885HSD17B10 521/4885ESR1 3138/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.