Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ATP4A | P20648 | 2/20 | 0.34 |
| ▸ | ATP4B | P51164 | 2/20 | 0.34 |
| ▸ | PPARG | P37231 | 3/20 | 0.31 |
| ▸ | PPARA | Q07869 | 3/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5567375 | 0.92 | ALDH1A1 (0.33) | ALDH1A1KDM4EATP4AATP4BPPARG | |
| SCHEMBL5567379 | 0.92 | ALDH1A1 (0.33) | ALDH1A1KDM4EATP4AATP4BPPARG | |
| SCHEMBL4600263 | 0.80 | ALDH1A1 (0.35) | ALDH1A1KDM4EATP4AATP4BPPARG | |
| SCHEMBL4600269 | 0.80 | ALDH1A1 (0.35) | ALDH1A1KDM4EATP4AATP4BPPARG | |
| SCHEMBL4600310 | 0.78 | ALDH1A1 (0.46) | ALDH1A1KDM4EATP4AATP4BPPARG | |
| SCHEMBL4600316 | 0.78 | ALDH1A1 (0.46) | ALDH1A1KDM4EATP4AATP4BPPARG | |
| SCHEMBL4600268 | 0.78 | ALDH1A1 (0.34) | ALDH1A1KDM4EATP4AATP4BPPARG | |
| SCHEMBL5569808 | 0.76 | KDM4E (0.36) | ALDH1A1KDM4EGAATSHRSMN1; SMN2 | |
| SCHEMBL4600465 | 0.73 | ALDH1A1 (0.36) | ALDH1A1KDM4EATP4AATP4BPPARG | |
| SCHEMBL4600457 | 0.73 | ALDH1A1 (0.36) | ALDH1A1KDM4EATP4AATP4BPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1696921-A1 | TRICYCLIC IMIDAZOPYRIDINES FOR USE AS GASTRIC SECRETION INHIBITORS | Altana Pharma AG (DE) | 2006-09-06 | — | — | EP | disclosed |
| WO-2005058325-A1 | TRICYCLIC IMIDAZOPYRIDINES FOR USE AS GASTRIC SECRETION INHIBITORS | ALTANA PHARMA AG (DE) | 2005-06-30 | — | — | WO | disclosed |