SCHEMBL5567375

SCHEMBL5567375

Cc1nc2c(O[Si](C)(C)C(C)(C)C(C)C)c(C/C=C/c3ccccc3)c(C(=O)N(C)C)cn2c1C

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.33
KDM4E B2RXH2 1/20 0.33
ATP4A P20648 2/20 0.32
ATP4B P51164 2/20 0.32
RAB9A P51151 1/20 0.30
PPARG P37231 1/20 0.30
PPARA Q07869 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5567379 1.00 ALDH1A1 (0.33) ALDH1A1KDM4EATP4AATP4BRAB9A
SCHEMBL6030977 0.92 ALDH1A1 (0.35) ALDH1A1KDM4EATP4AATP4BPPARG
SCHEMBL5569808 0.85 KDM4E (0.36) ALDH1A1KDM4E
SCHEMBL4979651 0.82 RIPK1 (0.31)
SCHEMBL4600103 0.82 ALDH1A1 (0.34) ALDH1A1KDM4EATP4AATP4BRAB9A
SCHEMBL5570709 0.81 ATP4A (0.40) ALDH1A1KDM4EATP4AATP4BRAB9A
SCHEMBL5570706 0.81 ATP4A (0.40) ALDH1A1KDM4EATP4AATP4BRAB9A
SCHEMBL4600661 0.80 ALDH1A1 (0.43) ALDH1A1KDM4EATP4AATP4BRAB9A
SCHEMBL4600666 0.80 ALDH1A1 (0.43) ALDH1A1KDM4EATP4AATP4BRAB9A
SCHEMBL5570220 0.75 PRKDC (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070066674-A1 Tricyclic imidzopyridines for use as gastric secretion inhibitors ALTANA PHARMA AG (DE) 2007-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070066674-A1 Tricyclic imidzopyridines for use as gastric secretion inhibitors GIPR, SLC10A2, GRPR ALDH1A1 1722/4885KDM4E 4244/4885ATP4A 96/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.