Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | CNR2 | P34972 | 4/20 | 0.50 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6031457 | 0.94 | ALDH1A1 (0.51) | ALDH1A1HPGDHSD17B10CNR2CYP26A1 | |
| SCHEMBL5449533 | 0.91 | ALDH1A1 (0.61) | ALDH1A1HPGDHSD17B10CNR2EGFR | |
| SCHEMBL6031618 | 0.87 | CYP26A1 (0.45) | ALDH1A1HPGDHSD17B10CNR2CYP26A1 | |
| SCHEMBL14496299 | 0.85 | ALDH1A1 (0.60) | ALDH1A1HPGDHSD17B10CNR2NPSR1 | |
| SCHEMBL6031470 | 0.84 | ALDH1A1 (0.49) | ALDH1A1HPGDHSD17B10CNR2CYP26A1 | |
| SCHEMBL6031292 | 0.82 | ALDH1A1 (0.45) | ALDH1A1HPGDHSD17B10CNR2CYP26A1 | |
| SCHEMBL6031563 | 0.80 | NR3C1 (0.50) | ALDH1A1HPGDHSD17B10CNR2CYP26A1 | |
| SCHEMBL1726248 | 0.78 | CHRM2 (0.38) | ALDH1A1HPGDCNR2EGFRERBB2 | |
| SCHEMBL13464286 | 0.78 | CA2 (0.60) | ALDH1A1HPGDHSD17B10CYP26A1LMNA | |
| SCHEMBL6032560 | 0.77 | CNR2 (0.47) | ALDH1A1CNR2EGFRERBB2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060052627-A1 | Novel modulators of the PPAR-type receptors and cosmetic/pharmaceutical compositions comprised thereof | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2006-03-09 | — | — | US | claimed |
| EP-1596853-A1 | COMPOUNDS WHICH ARE MODULATORS OF THE PPAR-TYPE RECEPTORS AND THEIR USE IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | Galderma Research & Development, S.N.C. (FR) | 2005-11-23 | — | — | EP | claimed |
| WO-2004071504-A1 | COMPOUNDS WHICH ARE MODULATORS OF THE PPAR-TYPE RECEPTORS AND THEIR USE IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2004-08-26 | — | — | WO | claimed |
| US-20060052627-A1 | Novel modulators of the PPAR-type receptors and cosmetic/pharmaceutical compositions comprised thereof | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2006-03-09 | — | — | US | disclosed |
| EP-1596853-A1 | COMPOUNDS WHICH ARE MODULATORS OF THE PPAR-TYPE RECEPTORS AND THEIR USE IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | Galderma Research & Development, S.N.C. (FR) | 2005-11-23 | — | — | EP | disclosed |
| WO-2004071504-A1 | COMPOUNDS WHICH ARE MODULATORS OF THE PPAR-TYPE RECEPTORS AND THEIR USE IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2004-08-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060052627-A1 | Novel modulators of the PPAR-type receptors and cosmetic/pharmaceutical compositions comprised thereof | PPARG, PPARD, PPARA | ALDH1A1 671/4885HPGD 589/4885HSD17B10 352/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.