Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 5/20 | 0.49 |
| ▸ | CES1 | P23141 | 2/20 | 0.49 |
| ▸ | P2RY10 | O00398 | 2/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | PLA2G4C | Q9UP65 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9116979 | 0.92 | CES2 (0.51) | FAAHCES1CES2MAPTMEN1 | |
| SCHEMBL9443027 | 0.81 | CES2 (0.46) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL29282406 | 0.79 | GRIK1 (0.44) | FAAHCES1CES2MAPTMEN1 | |
| SCHEMBL28283750 | 0.79 | GRIK1 (0.44) | FAAHCES1CES2MAPTMEN1 | |
| SCHEMBL2158216 | 0.78 | GRIK1 (0.42) | FAAHCES1CES2MAPTMEN1 | |
| SCHEMBL29029033 | 0.76 | FAAH (0.54) | FAAHCES1CES2ALDH1A1PLA2G4B | |
| SCHEMBL3963136 | 0.76 | GRIK1 (0.41) | FAAHCES1CES2MAPTMEN1 | |
| SCHEMBL28317076 | 0.76 | SLC1A2 (0.41) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL5597178 | 0.75 | CES2 (0.49) | CES2MAPTMEN1CYP1A2CYP3A4 | |
| SCHEMBL28365424 | 0.75 | FAAH (0.58) | FAAHCES1CES2ALDH1A1PLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115569151-A | Adipose tissue-derived stromal stem cells for the treatment of refractory, complex perianal fistulas in crohn's disease | 武田药品工业株式会社 | 2023-01-06 | — | — | CN | disclosed |
| CN-108883135-B | Adipose tissue-derived stromal stem cells for the treatment of refractory, complex perianal fistulas in crohn's disease | 武田药品工业株式会社 | 2022-11-04 | — | — | CN | disclosed |
| CN-106573017-B | Mesenchymal stromal cells for the treatment of sepsis | 泰根尼克斯独资有限公司 | 2021-06-11 | — | — | CN | disclosed |
| US-7070807-B2 | Branched histidine copolymers and methods for using same | MIXSON A JAMES | 2006-07-04 | — | — | US | disclosed |