Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 4/20 | 0.51 |
| ▸ | FAAH | O00519 | 8/20 | 0.41 |
| ▸ | CES1 | P23141 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.41 |
| ▸ | PLA2G2C | Q5R387 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6032015 | 0.92 | FAAH (0.49) | CES2FAAHCES1MEN1KMT2A | |
| SCHEMBL9443027 | 0.88 | CES2 (0.46) | CES2FAAHCES1MEN1KMT2A | |
| SCHEMBL28283750 | 0.86 | GRIK1 (0.44) | CES2FAAHCES1MEN1KMT2A | |
| SCHEMBL29282406 | 0.86 | GRIK1 (0.44) | CES2FAAHCES1MEN1KMT2A | |
| SCHEMBL2158216 | 0.84 | GRIK1 (0.42) | CES2FAAHCES1MEN1KMT2A | |
| SCHEMBL3963136 | 0.83 | GRIK1 (0.41) | CES2FAAHCES1MEN1KMT2A | |
| SCHEMBL28317076 | 0.82 | SLC1A2 (0.41) | CES2FAAHCES1MEN1KMT2A | |
| SCHEMBL11769413 | 0.81 | CES2 (0.49) | CES2MEN1KMT2ACYP1A2PLA2G2C | |
| SCHEMBL5597178 | 0.81 | CES2 (0.49) | CES2MEN1KMT2ACYP1A2PLA2G2C | |
| SCHEMBL3555667 | 0.79 | GRIK1 (0.33) | CES2FAAHCES1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995034641-A1 | STRUCTURAL MODELS FOR CYTOPLASMIC DOMAINS OF TRANSMEMBRANE RECEPTORS | THE SCRIPPS RESEARCH INSTITUTE (US) | 1995-12-21 | — | — | WO | disclosed |