Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 19/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8857258 | 0.81 | KDM4E (0.40) | KDM4EMAPT | |
| SCHEMBL8857435 | 0.79 | HPGD (0.41) | KDM4EMAPT | |
| SCHEMBL8857701 | 0.79 | KMT2A (0.52) | — | |
| SCHEMBL8657466 | 0.69 | MAPT (0.43) | KDM4EMAPT | |
| SCHEMBL8664520 | 0.68 | PPARG (0.56) | KDM4EMAPT | |
| SCHEMBL8472101 | 0.65 | MAPT (0.41) | KDM4EMAPT | |
| SCHEMBL8660907 | 0.65 | PPARG (0.53) | KDM4EMAPT | |
| SCHEMBL8687360 | 0.65 | PPARG (0.48) | KDM4EMAPT | |
| SCHEMBL22043230 | 0.65 | SIGMAR1 (1.00) | SIGMAR1 | |
| SCHEMBL18645287 | 0.65 | SIGMAR1 (1.00) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5925656-A | CONTAINING A 2,4-DIOXOTRIAZOLIDINE RING | DR. REDDY'S RESEARCH FOUNDATION (IN) | 1999-07-20 | — | — | US | claimed |
| US-5925656-A | CONTAINING A 2,4-DIOXOTRIAZOLIDINE RING | DR. REDDY'S RESEARCH FOUNDATION (IN) | 1999-07-20 | — | — | US | disclosed |