Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 5/20 | 0.32 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.30 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1336916 | 0.88 | MEN1 (0.42) | MEN1ALDH1A1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL6031443 | 0.81 | MEN1 (0.37) | MEN1ALDH1A1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL1336853 | 0.79 | P2RX7 (0.42) | MEN1ALDH1A1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL4484374 | 0.79 | LMNA (0.49) | MEN1ALDH1A1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL4477971 | 0.77 | AKR1B1 (0.40) | ALDH1A1LMNASMN1; SMN2HTTEGLN1 | |
| SCHEMBL6032420 | 0.76 | ALDH1A1 (0.46) | MEN1ALDH1A1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL4478273 | 0.76 | ALDH1A1 (0.46) | MEN1ALDH1A1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL4473406 | 0.76 | ALDH1A1 (0.42) | MEN1ALDH1A1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL4480309 | 0.76 | TNIK (0.37) | SMN1; SMN2EGLN1TNIK | |
| Trifluoroacetic Acid SCHEMBL4499510 | 0.75 | LMNA (0.46) | MEN1ALDH1A1KMT2ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1725556-A1 | HIV INTEGRASE INHIBITORS | Merck & Co., Inc. (US) | 2006-11-29 | — | — | EP | disclosed |
| WO-2005087768-A1 | HIV INTEGRASE INHIBITORS | MERCK & CO., INC. (US) | 2005-09-22 | — | — | WO | disclosed |
| WO-2005087767-A1 | HIV INTEGRASE INHIBITORS | MERCK & CO., INC. (US) | 2005-09-22 | — | — | WO | disclosed |