Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.30 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6033318 | 0.82 | SMN1; SMN2 (0.36) | NOS3NOS1NOS2LMNACYP3A4 | |
| SCHEMBL6032664 | 0.82 | TSHR (0.43) | NOS3NOS1NOS2LMNACYP3A4 | |
| SCHEMBL6033049 | 0.82 | MAPT (0.46) | NOS3NOS1NOS2LMNACYP3A4 | |
| SCHEMBL6033404 | 0.82 | ALDH1A1 (0.41) | NOS3NOS1NOS2LMNACYP3A4 | |
| SCHEMBL6033067 | 0.81 | ALDH1A1 (0.41) | NOS3NOS1NOS2LMNACYP3A4 | |
| SCHEMBL6033461 | 0.79 | MAPT (0.39) | NOS3NOS1NOS2LMNACYP3A4 | |
| SCHEMBL6033133 | 0.78 | PTGIR (0.43) | LMNACYP3A4CYP2D6TSHRRAB9A | |
| SCHEMBL6032640 | 0.76 | GFER (0.52) | LMNARAB9AMAPTKMT2AMEN1 | |
| SCHEMBL6033077 | 0.75 | HAO1 (0.40) | NOS3NOS1NOS2LMNARAB9A | |
| SCHEMBL6032678 | 0.71 | ALDH1A1 (0.38) | NOS3NOS1NOS2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7084137-B2 | Thiazines and thiazoles as agents for protecting materials | BAYER AKTIENGESELLSCHAFT (DE) | 2006-08-01 | — | — | US | claimed |