Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 2/20 | 0.37 |
| ▸ | FBP1 | P09467 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
| ▸ | DHFR | P00374 | 1/20 | 0.34 |
| ▸ | TYMS | P04818 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.33 |
| ▸ | SELE | P16581 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | USP7 | Q93009 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6033404 | 0.81 | ALDH1A1 (0.41) | HAO1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL6033042 | 0.79 | KDM4E (0.42) | GRM5FBP1MEN1KMT2ARAB9A | |
| SCHEMBL6032678 | 0.78 | ALDH1A1 (0.38) | MAPTDHFRTYMSNOS3NOS1 | |
| SCHEMBL6033364 | 0.76 | HPGD (0.38) | MEN1KMT2AMAPTTDP1PTPN11 | |
| SCHEMBL6033318 | 0.75 | SMN1; SMN2 (0.36) | HAO1FBP1MEN1KMT2ANPC1 | |
| SCHEMBL6032664 | 0.75 | TSHR (0.43) | FBP1MEN1KMT2ARAB9ALMNA | |
| SCHEMBL6032247 | 0.75 | NOS3 (0.35) | MEN1KMT2ARAB9ALMNAMAPT | |
| SCHEMBL6033067 | 0.74 | ALDH1A1 (0.41) | KMT2ARAB9ALMNAMAPTTDP1 | |
| SCHEMBL6033343 | 0.73 | PTGIR (0.38) | RAB9ALMNAMAPTNOS3NOS1 | |
| SCHEMBL6033315 | 0.73 | NOS3 (0.34) | MEN1KMT2ALMNAMAPTRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7084137-B2 | Thiazines and thiazoles as agents for protecting materials | BAYER AKTIENGESELLSCHAFT (DE) | 2006-08-01 | — | — | US | claimed |
| US-20040204405-A1 | Thiazines and thiazoles as agents for protecting materials | LANXESS DEUTSCHLAND GMBH (DE) | 2004-10-14 | — | — | US | claimed |
| EP-1437940-A1 | THIAZINES AND THIAZOLES FOR USE AS MATERIAL PROTECTIVE AGENTS | Bayer Chemicals AG (DE) | 2004-07-21 | — | — | EP | claimed |
| US-20030129081-A1 | Thiazines and thiazoles as agents for protecting materials | BAYER AKTIENGESELLSCHAFT (DE) | 2003-07-10 | — | — | US | claimed |
| WO-2003001913-A1 | THIAZINES AND THIAZOLES FOR USE AS MATERIAL PROTECTIVE AGENTS | BAYER CHEMICALS AG (DE) | 2003-01-09 | — | — | WO | claimed |
| JP-54145679-A | — | — | None | — | — | JP | disclosed |
| US-7084137-B2 | Thiazines and thiazoles as agents for protecting materials | BAYER AKTIENGESELLSCHAFT (DE) | 2006-08-01 | — | — | US | disclosed |
| US-20040204405-A1 | Thiazines and thiazoles as agents for protecting materials | LANXESS DEUTSCHLAND GMBH (DE) | 2004-10-14 | — | — | US | disclosed |
| US-20030129081-A1 | Thiazines and thiazoles as agents for protecting materials | BAYER AKTIENGESELLSCHAFT (DE) | 2003-07-10 | — | — | US | disclosed |
| JP-S54145679-A | 2-(DICHLOROPHENYLTHIO)-4,5-DIHYDRO-6H-1,3-THIAZINE | KURARAY CO LTD | 1979-11-14 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030129081-A1 | Thiazines and thiazoles as agents for protecting materials | POT1, NAT1, GPX1 | HAO1 840/4885GRM5 4216/4885FBP1 578/4885 |
| US-20040204405-A1 | Thiazines and thiazoles as agents for protecting materials | POT1, NAT1, GPX1 | HAO1 840/4885GRM5 4216/4885FBP1 578/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.