SCHEMBL6032487

SCHEMBL6032487

Cc1ccc(S(=O)(=O)Nc2ccc(O)c(-c3nc4ccccc4s3)c2)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 11/20 0.61
MEN1 O00255 6/20 0.61
KMT2A Q03164 6/20 0.61
KDM4E B2RXH2 3/20 0.61
RAB9A P51151 1/20 0.61
ALDH1A1 P00352 7/20 0.57
GAA P10253 7/20 0.57
HPGD P15428 3/20 0.57
GLA P06280 1/20 0.57
RORC P51449 1/20 0.57
LMNA P02545 6/20 0.56
HTT P42858 2/20 0.56
SMN1; SMN2 Q16637 2/20 0.56
POLB P06746 2/20 0.55
GFER P55789 1/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
ALOX12 P18054 1/20 0.54
NPSR1 Q6W5P4 1/20 0.54
MAPK1 P28482 1/20 0.54
TP53 P04637 4/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3679894 0.82 ALDH1A1 (0.78) MAPTMEN1KMT2AKDM4ERAB9A
SCHEMBL3737205 0.82 LMNA (0.62) MAPTKDM4EALDH1A1GAAHPGD
SCHEMBL16602315 0.80 MAPT (0.72) MAPTMEN1KMT2AKDM4ERAB9A
SCHEMBL2790890 0.79 MAPT (0.69) MAPTMEN1KMT2AKDM4ERAB9A
SCHEMBL13857585 0.78 MAPT (0.73) MAPTMEN1KMT2AKDM4ERAB9A
SCHEMBL27769428 0.78 MAPT (0.68) MAPTMEN1KMT2AKDM4ERAB9A
SCHEMBL2246115 0.76 MAPT (1.00) MAPTMEN1KMT2AKDM4ERAB9A
SCHEMBL5974825 0.76 MAPT (0.61) MAPTMEN1KMT2AKDM4ERAB9A
SCHEMBL5974820 0.76 MAPT (0.61) MAPTMEN1KMT2AKDM4ERAB9A
SCHEMBL13855422 0.75 MAPT (0.68) MAPTMEN1KMT2AKDM4ERAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7144738-B2 Materials for enhancing staining of biopolymers in matrices WHITNEY SCOTT 2006-12-05 US disclosed
US-20050170517-A1 Materials for enhancing staining of biopolymers in matrices INVITROGEN CORPORATION (US) 2005-08-04 US disclosed
US-6878551-B2 For proteins/polypeptides within polyacrylamide matrix; mass spectrometry INVITROGEN CORPORATION (US) 2005-04-12 US disclosed
US-20040038418-A1 Materials for enhancing staining of biopolymers in matrices INVITROGEN CORPORATION 2004-02-26 US disclosed
US-6635489-B2 Sensitizing the matrix with heteroaromatic compounds, contacting with reduceable metal salts to stain and detecting INVITROGEN CORPORATION 2003-10-21 US disclosed
US-20020137222-A1 Materials for enhancing staining of biopolymers in matrices INVITROGEN CORPORATION 2002-09-26 US disclosed