Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ3 | O43525 | 14/20 | 0.38 |
| ▸ | KCNQ2 | O43526 | 14/20 | 0.38 |
| ▸ | KCNE1 | P15382 | 9/20 | 0.38 |
| ▸ | KCNQ1 | P51787 | 9/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12724241 | 0.87 | CDK9 (0.40) | KCNQ3KCNQ2KCNE1KCNQ1ABL1 | |
| SCHEMBL6032081 | 0.84 | NPC1 (0.39) | ABL1KDM4ELMNANPC1RAB9A | |
| SCHEMBL6032115 | 0.79 | ABL1 (0.39) | KCNQ3KCNQ2KCNE1KCNQ1MAOB | |
| SCHEMBL1632916 | 0.79 | KCNQ3 (0.33) | KCNQ3KCNQ2KCNE1KCNQ1MDM2 | |
| SCHEMBL1631982 | 0.77 | ALDH1A1 (0.33) | KCNQ3KCNQ2 | |
| SCHEMBL1633549 | 0.77 | DPP4 (0.34) | KCNQ3KCNQ2KCNE1KCNQ1MDM2 | |
| SCHEMBL1632373 | 0.76 | PSEN1 (0.36) | MDM2 | |
| SCHEMBL12724236 | 0.75 | CDK9 (0.38) | KCNQ3KCNQ2ABL1KDM4ENPC1 | |
| SCHEMBL1632265 | 0.75 | CCNT1 (0.41) | ABL1 | |
| SCHEMBL1633359 | 0.74 | ABL1 (0.40) | ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1640366-A1 | HETEROCYCLIC METHYL SULFONE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-03-29 | — | — | EP | disclosed |