Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 7/20 | 0.56 |
| ▸ | EBP | Q15125 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.56 |
| ▸ | DRD3 | P35462 | 3/20 | 0.56 |
| ▸ | HTR6 | P50406 | 3/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15570846 | 1.00 | ESR1 (0.56) | ESR1EBPKMT2AMAPTADORA3 | |
| SCHEMBL6768538 | 0.95 | ESR1 (0.52) | ESR1EBPKMT2AMAPTADORA3 | |
| SCHEMBL4300358 | 0.79 | KMT2A (0.61) | KMT2AMAPTKCNH2ADRA2AADRA2B | |
| SCHEMBL7602287 | 0.79 | ESR1 (0.46) | ESR1EBPKMT2AMAPTADORA3 | |
| SCHEMBL7602301 | 0.79 | ESR1 (0.46) | ESR1EBPKMT2AMAPTADORA3 | |
| SCHEMBL27467107 | 0.79 | ESR1 (0.49) | ESR1EBPKMT2AMAPTADORA3 | |
| SCHEMBL6901842 | 0.78 | ESR1 (0.61) | ESR1EBPKMT2AMAPTADORA3 | |
| SCHEMBL10429856 | 0.78 | ADRA2A (0.43) | KCNH2ADRA2APTGS1SLC6A4KDM4E | |
| SCHEMBL27548651 | 0.78 | ESR1 (0.64) | ESR1EBPKMT2AMAPTADORA3 | |
| SCHEMBL27485629 | 0.78 | ESR1 (0.64) | ESR1EBPKMT2AMAPTADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1660072-A2 | MEANS AND METHODS FOR TREATING A DISEASE WHICH IS ASSOCIATED WITH AN EXCESS TRANSPORT OF HYALURONAN ACROSS A LIPID BILAYER | Universitätsklinikum Münster (DE) | 2006-05-31 | — | — | EP | disclosed |
| WO-2005013947-A2 | MEANS AND METHODS FOR TREATING A DISEASE WHICH IS ASSOCIATED WITH AN EXCESS TRANSPORT OF HYALURONAN ACROSS A LIPID BILAYER | Universitätsklinikum Münster (DE) | 2005-02-17 | — | — | WO | disclosed |