Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 4/20 | 0.40 |
| ▸ | RARB | P10826 | 4/20 | 0.40 |
| ▸ | RARG | P13631 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 14/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.39 |
| ▸ | HNF4A | P41235 | 4/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.34 |
| ▸ | RXRG | P48443 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6033101 | 0.90 | RXRA (0.47) | RARARARBRARGCYP3A4RXRA | |
| SCHEMBL6032738 | 0.89 | RARA (0.38) | RARARARBRARGCYP3A4KMT2A | |
| SCHEMBL6032605 | 0.86 | RXRA (0.48) | RARARARBRARGCYP3A4KMT2A | |
| SCHEMBL6033253 | 0.85 | RARA (0.41) | RARARARBRARGCYP3A4KMT2A | |
| SCHEMBL6032646 | 0.85 | RARA (0.43) | RARARARBRARGCYP3A4KMT2A | |
| SCHEMBL6033270 | 0.84 | RARA (0.43) | RARARARBRARGCYP3A4KMT2A | |
| SCHEMBL6033326 | 0.82 | RARA (0.37) | RARARARBRARGCYP3A4KMT2A | |
| SCHEMBL6032626 | 0.80 | RARG (0.49) | RARARARBRARGCYP3A4KMT2A | |
| SCHEMBL6033264 | 0.79 | RARA (0.48) | RARARARBRARGCYP3A4KMT2A | |
| SCHEMBL6032986 | 0.79 | RXRA (0.59) | RXRAPPARGNR1H3HNF4ARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6992094-B1 | Diarylselenide compounds and their use in human or veterinary medicine and in cosmetics | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2006-01-31 | — | — | US | disclosed |
| US-20060014803-A1 | Diarylselenide compounds and their use in human or veterinary medicine and in cosmetics | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2006-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060014803-A1 | Diarylselenide compounds and their use in human or veterinary medicine and in cosmetics | TYR, DERL1, GPX1 | RARA 2083/4885RARB 2125/4885RARG 2050/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.