Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 15/20 | 0.56 |
| ▸ | RXRB | P28702 | 13/20 | 0.56 |
| ▸ | RXRG | P48443 | 11/20 | 0.56 |
| ▸ | RARB | P10826 | 8/20 | 0.56 |
| ▸ | RARG | P13631 | 7/20 | 0.56 |
| ▸ | RARA | P10276 | 6/20 | 0.53 |
| ▸ | CYP26A1 | O43174 | 4/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | CYP26B1 | Q9NR63 | 2/20 | 0.52 |
| ▸ | CRABP2 | P29373 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6033065 | 0.83 | RXRA (0.66) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL4956919 | 0.81 | RXRA (0.51) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL6033044 | 0.81 | RXRA (0.59) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL6878104 | 0.78 | RXRA (0.51) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL7670810 | 0.78 | RXRA (0.51) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL29827631 | 0.78 | RARB (0.81) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL846110 | 0.78 | RARB (0.81) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL6033014 | 0.78 | RARG (0.45) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL6033247 | 0.77 | GCK (0.42) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL6033132 | 0.76 | RARB (0.56) | RXRARXRBRXRGRARBRARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6992094-B1 | Diarylselenide compounds and their use in human or veterinary medicine and in cosmetics | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2006-01-31 | — | — | US | claimed |
| EP-1086080-B1 | DIARYLSELENIDE COMPOUNDS AND THEIR USE IN HUMAN OR VETERINARY MEDICINE AND IN COSMETICS | GALDERMA RES & DEV (FR) | 2004-08-25 | — | — | EP | claimed |
| US-6992094-B1 | Diarylselenide compounds and their use in human or veterinary medicine and in cosmetics | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2006-01-31 | — | — | US | disclosed |
| US-20060014803-A1 | Diarylselenide compounds and their use in human or veterinary medicine and in cosmetics | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2006-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060014803-A1 | Diarylselenide compounds and their use in human or veterinary medicine and in cosmetics | TYR, DERL1, GPX1 | RXRA 1865/4885RXRB 1881/4885RXRG 1599/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.