Biotin

Biotin

SCHEMBL6033491

CCCCCC(=O)O.O=C(O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@@H]21

nearest known ligand 0.87

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 6/20 0.87
MEN1 O00255 1/20 0.87
ABL1 P00519 1/20 0.87
LMNA P02545 1/20 0.87
PKM P14618 1/20 0.87
IDE P14735 1/20 0.87
MAPK1 P28482 1/20 0.87
KMT2A Q03164 1/20 0.87
RIN1 Q13671 1/20 0.87
L3MBTL1 Q9Y468 1/20 0.87
HLCS P50747 6/20 0.80
CA12 O43570 5/20 0.51
CA1 P00915 5/20 0.51
CA2 P00918 5/20 0.51
CA9 Q16790 5/20 0.51
F2 P00734 1/20 0.48
PRSS1 P07477 1/20 0.48
PRSS2 P07478 1/20 0.48
PRSS3 P35030 1/20 0.48
TPSAB1 Q15661 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biotin SCHEMBL8651197 1.00 TDP1 (0.87) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL8672968 0.99 TDP1 (0.85) TDP1MEN1ABL1LMNAPKM
Stearic Acid SCHEMBL10828834 0.97 TDP1 (0.83) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL27671459 0.97 TDP1 (0.87) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL3518095 0.97 TDP1 (0.87) TDP1MEN1ABL1LMNAPKM
Hexanoate SCHEMBL4243024 0.95 TDP1 (0.79) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL987288 0.95 TDP1 (0.79) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL6704836 0.95 TDP1 (0.87) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL715457 0.94 TDP1 (0.77) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL27711773 0.94 TDP1 (0.77) TDP1MEN1ABL1LMNAPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119986016-A Dopamine chemiluminescence immunoassay kit 天津市协和化学发光诊断试剂有限公司 2025-05-13 CN disclosed
WO-2012049464-A1 REAGENT THE UNIVERSITY OF BATH, BATH VENTURES (GB) 2012-04-19 WO disclosed
US-7078013-B2 Pretargeting methods and compounds ALETHEON PHARMACEUTICALS, INC. (US) 2006-07-18 US disclosed
US-20060148124-A1 Nanoparticle conjugates and method of production thereof THE UNIVERSITY OF LIVERPOOL (GB) 2006-07-06 US disclosed
EP-1565216-A1 NANOPARTICLE CONJUGATES AND METHOD OF PRODUCTION THEREOF THE UNIVERSITY OF LIVERPOOL (GB) 2005-08-24 EP disclosed
US-20040241172-A1 Pretargeting methods and compounds NEORX CORPORATION (US) 2004-12-02 US disclosed
WO-2004047870-A1 NANOPARTICLE CONJUGATES AND METHOD OF PRODUCTION THEREOF THE UNIVERSITY OF LIVERPOOL (GB) 2004-06-10 WO disclosed
US-6709652-B2 RADIOACTIVE LABELING OF BIOTIN NEORX CORPORATION 2004-03-23 US disclosed
EP-1346730-A1 Pretargeting methods and novel pretargeting conjugates NEORX CORPORATION (US) 2003-09-24 EP disclosed
US-20030129191-A1 Pretargeting methods and compounds NEORX CORPORATION (US) 2003-07-10 US disclosed
EP-0733066-A1 PRETARGETING METHODS AND COMPOUNDS NEORX CORPORATION (US) 1996-09-25 EP disclosed
US-5541287-A DIAGNOSIS USING CYCLIC TRIPEPTIDES WITH NITROBENZYL 1,4,7,10-TETRAAZACYCLODODECANE-N,N*,N**,N***TETRAACETIC ACID BIOTIN CONJUGATE FORMED BY ALKYLATION AND MULTISTAGE PROCESS NEORX CORPORATION (US) 1996-07-30 US disclosed
WO-1995015978-A1 PRETARGETING METHODS AND COMPOUNDS NEORX CORPORATION (US) 1995-06-15 WO disclosed
WO-1995015770-A1 PRETARGETING METHODS AND COMPOUNDS NEORX CORPORATION (US) 1995-06-15 WO disclosed
WO-1995015979-A1 PRETARGETING METHODS AND COMPOUNDS NEORX CORPORATION (US) 1995-06-15 WO disclosed
WO-1995015335-A2 PRETARGETING METHODS AND COMPOUNDS NEORX CORPORATION (US) 1995-06-08 WO disclosed
EP-0646019-A1 PRETARGETING METHODS AND COMPOUNDS NEORX CORPORATION (US) 1995-04-05 EP disclosed
EP-0629292-A1 METHOD FOR MAKING A PRECONJUGATE BECKMAN INSTRUMENTS, INC. (US) 1994-12-21 EP disclosed
WO-1994016330-A1 METHOD FOR MAKING A PRECONJUGATE BECKMAN INSTRUMENTS, INC. (US) 1994-07-21 WO disclosed
WO-1993025240-A2 PRETARGETING METHODS AND COMPOUNDS NEORX CORPORATION (US) 1993-12-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040241172-A1 Pretargeting methods and compounds HLCS, BTD, STRA6 TDP1 3824/4885MEN1 723/4885ABL1 3654/4885
US-20030129191-A1 Pretargeting methods and compounds BTD, HLCS, STRA6 TDP1 3339/4885MEN1 496/4885ABL1 3294/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.