Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CENPE | Q02224 | 3/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.38 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 3/20 | 0.37 |
| ▸ | KIFC1 | Q9BW19 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 4/20 | 0.33 |
| ▸ | WDR5 | P61964 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2103853 | 1.00 | CENPE (0.72) | CENPEALDH1A1ALDH1A2ALDH1A3PPARG | |
| SCHEMBL2102545 | 0.93 | CENPE (0.63) | CENPEALDH1A1ALDH1A2ALDH1A3PPARG | |
| SCHEMBL2105538 | 0.92 | CENPE (0.60) | CENPEALDH1A1ALDH1A2ALDH1A3PPARG | |
| SCHEMBL4553500 | 0.92 | CENPE (0.60) | CENPEALDH1A1ALDH1A2ALDH1A3PPARG | |
| SCHEMBL2617330 | 0.89 | CENPE (0.79) | CENPEALDH1A1ALDH1A2ALDH1A3PPARG | |
| SCHEMBL2104360 | 0.88 | CENPE (0.78) | CENPEALDH1A1ALDH1A2ALDH1A3PPARG | |
| SCHEMBL3213358 | 0.88 | CENPE (0.77) | CENPEALDH1A1ALDH1A2ALDH1A3PPARG | |
| SCHEMBL2103186 | 0.88 | CENPE (0.77) | CENPEALDH1A1ALDH1A2ALDH1A3PPARG | |
| SCHEMBL360385 | 0.88 | CENPE (0.77) | CENPEALDH1A1ALDH1A2ALDH1A3PPARG | |
| SCHEMBL4428105 | 0.88 | CENPE (0.77) | CENPEALDH1A1ALDH1A2ALDH1A3PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060247289-A1 | Certain chemical entities, compositions, and methods | CYTOKINETICS, INCORPORATED | 2006-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060247289-A1 | Certain chemical entities, compositions, and methods | KIF5B, KIF2C, PLK1 | CENPE 54/4885ALDH1A1 2159/4885ALDH1A2 860/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.