Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CCNC | P24863 | 1/20 | 0.35 |
| ▸ | CDK8 | P49336 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 2/20 | 0.35 |
| ▸ | ACACA | Q13085 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6033534 | 0.99 | KMT2A (0.38) | MAPTPTGS2THRBTP53KMT2A | |
| SCHEMBL12731097 | 0.89 | MAPT (0.45) | MAPTTHRBTP53KMT2ACCNC | |
| SCHEMBL14507240 | 0.88 | KMT2A (0.47) | MAPTTHRBTP53KMT2ACCNC | |
| SCHEMBL5961761 | 0.87 | TP53 (0.43) | MAPTTHRBTP53KMT2A | |
| SCHEMBL5961774 | 0.86 | THRB (0.43) | MAPTTHRBTP53KMT2A | |
| SCHEMBL10071027 | 0.79 | HIF1A (0.34) | MAPTKMT2AHIF1A | |
| SCHEMBL10120919 | 0.79 | KMT2A (0.56) | MAPTPTGS2THRBTP53KMT2A | |
| SCHEMBL10071953 | 0.75 | RXRA (0.41) | MAPTPTGS2TP53KMT2AACACB | |
| SCHEMBL14507437 | 0.75 | MAPT (0.51) | MAPTTP53KMT2ATSHR | |
| SCHEMBL13206937 | 0.75 | ALDH1A1 (0.41) | MAPTTP53KMT2ACCNCCDK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7919648-B2 | Lateral α-substituted acrylate compound and polymer thereof | CHISSO CORPORATION (JP) | 2011-04-05 | — | — | US | disclosed |