SCHEMBL6034293

SCHEMBL6034293

CN(CCCCC(=O)c1ccc2c(c1)NC(=O)CO2)CCc1ccccc1Cl

nearest known ligand 0.53

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CASP3 P42574 1/20 0.53
SENP7 Q9BQF6 1/20 0.53
ALDH1A1 P00352 8/20 0.52
MAPT P10636 8/20 0.52
RXFP1 Q9HBX9 2/20 0.49
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
KDM4E B2RXH2 2/20 0.47
POLB P06746 2/20 0.46
USP2 O75604 1/20 0.46
BLM P54132 1/20 0.46
LMNA P02545 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
GAA P10253 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL4862137 0.99 CASP3 (0.52) CASP3SENP7ALDH1A1MAPTRXFP1
SCHEMBL6035070 0.99 ALDH1A1 (0.52) CASP3SENP7ALDH1A1MAPTRXFP1
Hydrochloric Acid SCHEMBL4854858 0.98 ALDH1A1 (0.51) CASP3SENP7ALDH1A1MAPTRXFP1
SCHEMBL6035021 0.89 ALDH1A1 (0.58) CASP3SENP7ALDH1A1MAPTRXFP1
SCHEMBL6034254 0.89 ALDH1A1 (0.57) CASP3SENP7ALDH1A1MAPTRXFP1
Hydrochloric Acid SCHEMBL4858447 0.89 ALDH1A1 (0.57) CASP3SENP7ALDH1A1MAPTRXFP1
SCHEMBL4861331 0.89 CASP3 (0.54) CASP3SENP7ALDH1A1MAPTRXFP1
SCHEMBL6034890 0.88 ALDH1A1 (0.51) CASP3SENP7ALDH1A1MAPTRXFP1
Hydrochloric Acid SCHEMBL4850578 0.88 ALDH1A1 (0.56) CASP3SENP7ALDH1A1MAPTRXFP1
SCHEMBL4855307 0.88 CASP3 (0.54) CASP3SENP7ALDH1A1MAPTRXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7462628-B2 Preventives/remedies for urinary disturbance TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2008-12-09 US disclosed
US-7462628-B2 Preventives/remedies for urinary disturbance TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2008-12-09 US disclosed
US-20060063769-A1 Preventives/remedies for urinary disturbance TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2006-03-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060063769-A1 Preventives/remedies for urinary disturbance ACHE, BPHL, CHRM1 CASP3 2953/4885SENP7 858/4885ALDH1A1 118/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.