Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 11/20 | 0.48 |
| ▸ | PPARG | P37231 | 2/20 | 0.48 |
| ▸ | PPARA | Q07869 | 3/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | GCGR | P47871 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6035082 | 0.88 | PPARD (0.52) | PPARDPPARGPPARAPTGDR2FFAR4 | |
| SCHEMBL6035033 | 0.87 | PPARA (0.52) | PPARDPPARGPPARASMN1; SMN2HPGD | |
| SCHEMBL6035888 | 0.84 | PPARD (0.55) | PPARDPPARGPPARAFFAR4FFAR1 | |
| SCHEMBL6036002 | 0.83 | NR1H2 (0.45) | PPARDPPARGPPARAPTGDR2SMN1; SMN2 | |
| SCHEMBL6036359 | 0.82 | FFAR1 (0.47) | PPARDPPARGPPARAFFAR4FFAR1 | |
| SCHEMBL6035594 | 0.82 | FFAR1 (0.45) | PPARDPPARGPPARASMN1; SMN2HPGD | |
| SCHEMBL6218738 | 0.81 | SMN1; SMN2 (0.44) | SMN1; SMN2HPGDNPC1MAPTRAB9A | |
| SCHEMBL6035801 | 0.80 | PPARD (0.45) | PPARDPPARGPPARASMN1; SMN2HPGD | |
| SCHEMBL3451544 | 0.79 | ITGB3 (0.46) | PPARDPPARGPPARASMN1; SMN2HPGD | |
| SCHEMBL6035450 | 0.78 | FFAR1 (0.37) | PPARDPPARGPPARASMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060148858-A1 | 1, 2-Azole derivatives with hypoglycemic and hypolipidemic activity | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060148858-A1 | 1, 2-Azole derivatives with hypoglycemic and hypolipidemic activity | GPR119, SLC5A1, CYP4B1 | PPARD 2488/4885PPARG 1037/4885PPARA 1717/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.