SCHEMBL6036359

SCHEMBL6036359

COc1cc(OCc2cn(-c3ccc(C(F)(F)F)cn3)nc2C)ccc1CCC(=O)O

nearest known ligand 0.47

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 13/20 0.47
PPARD Q03181 5/20 0.47
PPARG P37231 3/20 0.46
PPARA Q07869 3/20 0.46
FFAR4 Q5NUL3 2/20 0.44
FFAR2 O15552 1/20 0.44
RXRA P19793 1/20 0.39
NR1H2 P55055 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6035594 0.92 FFAR1 (0.45) FFAR1PPARDPPARGPPARAFFAR4
SCHEMBL6035888 0.91 PPARD (0.55) FFAR1PPARDPPARGPPARAFFAR4
SCHEMBL6036288 0.89 FFAR1 (0.43) FFAR1PPARDPPARGPPARAFFAR4
SCHEMBL6035082 0.87 PPARD (0.52) FFAR1PPARDPPARGPPARAFFAR4
SCHEMBL6035648 0.84 PPARG (0.43) FFAR1PPARDPPARGPPARA
SCHEMBL6035657 0.83 PPARG (0.43) FFAR1PPARDPPARGPPARAFFAR4
SCHEMBL6035581 0.83 PPARG (0.43) FFAR1PPARDPPARGPPARA
SCHEMBL6035914 0.83 PPARG (0.43) FFAR1PPARDPPARGPPARA
SCHEMBL6034690 0.82 PPARD (0.48) FFAR1PPARDPPARGPPARAFFAR4
SCHEMBL6035153 0.82 PPARG (0.40) FFAR1PPARDPPARGPPARAFFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060148858-A1 1, 2-Azole derivatives with hypoglycemic and hypolipidemic activity TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2006-07-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060148858-A1 1, 2-Azole derivatives with hypoglycemic and hypolipidemic activity GPR119, SLC5A1, CYP4B1 FFAR1 376/4885PPARD 2488/4885PPARG 1037/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.