Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 8/20 | 0.41 |
| ▸ | PPARA | Q07869 | 7/20 | 0.38 |
| ▸ | PPARD | Q03181 | 4/20 | 0.38 |
| ▸ | SLC16A3 | O15427 | 4/20 | 0.37 |
| ▸ | SLC16A1 | P53985 | 4/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.36 |
| ▸ | MCTS1 | Q9ULC4 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6034824 | 0.91 | PPARG (0.34) | PPARGPPARAPPARDSLC16A3SLC16A1 | |
| SCHEMBL6034655 | 0.90 | PPARG (0.40) | PPARGPPARAPPARDSLC16A3SLC16A1 | |
| SCHEMBL6035708 | 0.85 | PPARA (0.43) | PPARGPPARAPPARD | |
| SCHEMBL6034478 | 0.85 | PPARA (0.41) | PPARGPPARAPPARDSLC16A3SLC16A1 | |
| SCHEMBL6034895 | 0.83 | PPARG (0.43) | PPARGPPARAPPARDSLC16A3SLC16A1 | |
| SCHEMBL6034688 | 0.83 | PPARA (0.40) | PPARGPPARAPPARDFFAR1CYP4F2 | |
| SCHEMBL6035775 | 0.82 | PPARG (0.41) | PPARGPPARAPPARDSLC16A3SLC16A1 | |
| SCHEMBL6035146 | 0.82 | PPARG (0.44) | PPARGPPARAPPARDSLC16A3SLC16A1 | |
| SCHEMBL6034648 | 0.82 | DGAT1 (0.35) | PPARGPPARAPPARDSLC16A3SLC16A1 | |
| SCHEMBL1634400 | 0.82 | PPARA (0.40) | PPARGPPARAPPARDCYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060148858-A1 | 1, 2-Azole derivatives with hypoglycemic and hypolipidemic activity | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060148858-A1 | 1, 2-Azole derivatives with hypoglycemic and hypolipidemic activity | GPR119, SLC5A1, CYP4B1 | PPARG 1037/4885PPARA 1717/4885PPARD 2488/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.