Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 2/20 | 0.61 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.61 |
| ▸ | MAOB | P27338 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.54 |
| ▸ | PPARG | P37231 | 1/20 | 0.54 |
| ▸ | PPARD | Q03181 | 1/20 | 0.54 |
| ▸ | PPARA | Q07869 | 1/20 | 0.54 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2957881 | 0.92 | MEN1 (0.67) | LTB4RLTB4R2MAOBMEN1KMT2A | |
| SCHEMBL16348239 | 0.91 | MEN1 (0.65) | LTB4RLTB4R2MAOBMEN1KMT2A | |
| SCHEMBL9205498 | 0.89 | LTB4R (0.68) | LTB4RLTB4R2MAOBMEN1KMT2A | |
| SCHEMBL3569849 | 0.86 | PPARD (0.56) | LTB4RLTB4R2FFAR1PPARGPPARD | |
| SCHEMBL3566811 | 0.85 | FFAR1 (0.59) | LTB4RLTB4R2MAOBFFAR1PPARG | |
| SCHEMBL23906959 | 0.85 | MAOB (0.79) | MAOBMEN1KMT2AMRGPRX4L3MBTL1 | |
| SCHEMBL1592559 | 0.84 | LTB4R (0.60) | LTB4RLTB4R2MAOBMEN1KMT2A | |
| SCHEMBL5132262 | 0.84 | PLA2G4B (0.57) | LTB4RLTB4R2MAOBMEN1KMT2A | |
| SCHEMBL347352 | 0.83 | PTGS1 (0.59) | MEN1KMT2APPARGL3MBTL1NFKB1 | |
| SCHEMBL340452 | 0.83 | MEN1 (0.84) | MAOBMEN1KMT2AMRGPRX4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080249137-A1 | PPAR active compounds | PLEXXIKON INC | 2008-10-09 | — | — | US | disclosed |
| US-20080249137-A1 | PPAR active compounds | PLEXXIKON INC | 2008-10-09 | — | — | US | disclosed |
| WO-2007030567-A2 | PPARACTIVE COMPOUNDS | PLEXXIKON, INC. (US) | 2007-03-15 | — | — | WO | disclosed |
| US-20060148858-A1 | 1, 2-Azole derivatives with hypoglycemic and hypolipidemic activity | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080249137-A1 | PPAR active compounds | PPARG, PPARA, PPARD | LTB4R 1352/4885LTB4R2 1188/4885MAOB 3838/4885 |
| US-20060148858-A1 | 1, 2-Azole derivatives with hypoglycemic and hypolipidemic activity | GPR119, SLC5A1, CYP4B1 | LTB4R 1376/4885LTB4R2 1747/4885MAOB 954/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.