SCHEMBL16348239

SCHEMBL16348239

O=C(O)Cc1cc(OCc2cc(OCc3ccccc3)cc(OCc3ccccc3)c2)cc(OCc2cc(OCc3ccccc3)cc(OCc3ccccc3)c2)c1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.65
KMT2A Q03164 1/20 0.65
LTB4R Q15722 2/20 0.63
LTB4R2 Q9NPC1 2/20 0.63
AKR1B1 P15121 1/20 0.53
NR4A2 P43354 2/20 0.53
NR4A1 P22736 1/20 0.53
NR4A3 Q92570 1/20 0.53
FFAR1 O14842 3/20 0.53
FFAR4 Q5NUL3 1/20 0.53
PPARG P37231 1/20 0.53
PPARD Q03181 1/20 0.53
MAOB P27338 2/20 0.50
PARP10 Q53GL7 1/20 0.50
CYP4F2 P78329 1/20 0.50
CYP4A11 Q02928 1/20 0.50
LMNA P02545 1/20 0.50
CYP1A2 P05177 1/20 0.50
PTGS1 P23219 1/20 0.50
SLC6A2 P23975 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2957881 0.98 MEN1 (0.67) MEN1KMT2ALTB4RLTB4R2AKR1B1
SCHEMBL9205498 0.95 LTB4R (0.68) MEN1KMT2ALTB4RLTB4R2AKR1B1
SCHEMBL6035486 0.91 LTB4R (0.61) MEN1KMT2ALTB4RLTB4R2FFAR1
SCHEMBL1592559 0.90 LTB4R (0.60) MEN1KMT2ALTB4RLTB4R2AKR1B1
SCHEMBL9205647 0.88 MEN1 (0.67) MEN1KMT2ALTB4RLTB4R2NR4A2
SCHEMBL3569632 0.87 PPARG (0.62) MEN1KMT2ALTB4RLTB4R2AKR1B1
SCHEMBL135152 0.87 LTB4R (0.57) MEN1KMT2ALTB4RLTB4R2AKR1B1
SCHEMBL137942 0.87 LTB4R (0.57) MEN1KMT2ALTB4RLTB4R2AKR1B1
SCHEMBL5132262 0.87 PLA2G4B (0.57) MEN1KMT2ALTB4RLTB4R2PPARG
SCHEMBL954459 0.86 NR4A2 (0.66) KMT2ALTB4RLTB4R2NR4A2FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7297298-B2 Nano-particles and process for producing nano-particles FUJIFILM CORPORATION (JP) 2007-11-20 US disclosed
US-7297298-B2 Nano-particles and process for producing nano-particles FUJIFILM CORPORATION (JP) 2007-11-20 US disclosed