Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 5/20 | 0.60 |
| ▸ | PTGER2 | P43116 | 5/20 | 0.60 |
| ▸ | PTGER3 | P43115 | 4/20 | 0.60 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.52 |
| ▸ | RXRA | P19793 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | APP | P05067 | 2/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6035782 | 1.00 | PTGER4 (0.60) | PTGER4PTGER2PTGER3PTGER1KDM4E | |
| SCHEMBL16265416 | 0.85 | ABCG2 (0.69) | KDM4ELMNAABCG2ALDH1A1PKM | |
| SCHEMBL16265418 | 0.85 | ABCG2 (0.69) | KDM4ELMNAABCG2ALDH1A1PKM | |
| SCHEMBL4262496 | 0.85 | ALDH1A1 (0.58) | PTGER4PTGER2PTGER3PTGER1KDM4E | |
| SCHEMBL21957672 | 0.85 | HDAC8 (0.58) | PTGER4PTGER2PTGER3PTGER1KDM4E | |
| SCHEMBL4262500 | 0.85 | ALDH1A1 (0.58) | PTGER4PTGER2PTGER3PTGER1KDM4E | |
| SCHEMBL10870465 | 0.84 | PTGER1 (0.54) | PTGER4PTGER2PTGER3PTGER1KDM4E | |
| SCHEMBL10870470 | 0.84 | PTGER1 (0.54) | PTGER4PTGER2PTGER3PTGER1KDM4E | |
| SCHEMBL4981344 | 0.81 | MAPT (0.51) | ABCG2RXRAMRGPRX4ATMAPP | |
| SCHEMBL4981349 | 0.81 | MAPT (0.51) | ABCG2RXRAMRGPRX4ATMAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060148858-A1 | 1, 2-Azole derivatives with hypoglycemic and hypolipidemic activity | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060148858-A1 | 1, 2-Azole derivatives with hypoglycemic and hypolipidemic activity | GPR119, SLC5A1, CYP4B1 | PTGER4 2147/4885PTGER2 4649/4885PTGER3 4074/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.