Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | PTGER4 | P35408 | 4/20 | 0.55 |
| ▸ | PTGER2 | P43116 | 4/20 | 0.55 |
| ▸ | PTGER3 | P43115 | 4/20 | 0.52 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | GSK3B | P49841 | 2/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.49 |
| ▸ | APP | P05067 | 2/20 | 0.49 |
| ▸ | BACE1 | P56817 | 1/20 | 0.49 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.49 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4262496 | 1.00 | ALDH1A1 (0.58) | ALDH1A1KDM4EPKMSMN1; SMN2PTGER4 | |
| SCHEMBL21957672 | 0.89 | HDAC8 (0.58) | ALDH1A1KDM4EPKMSMN1; SMN2PTGER4 | |
| SCHEMBL1745061 | 0.86 | HDAC8 (0.53) | LMNAHDAC8GSK3BAPP | |
| SCHEMBL1745060 | 0.86 | HDAC8 (0.53) | LMNAHDAC8GSK3BAPP | |
| SCHEMBL6035782 | 0.85 | PTGER4 (0.60) | ALDH1A1KDM4EPKMSMN1; SMN2PTGER4 | |
| SCHEMBL6035778 | 0.85 | PTGER4 (0.60) | ALDH1A1KDM4EPKMSMN1; SMN2PTGER4 | |
| SCHEMBL18538447 | 0.84 | HDAC8 (0.65) | ALDH1A1KDM4EPKMSMN1; SMN2PTGER4 | |
| SCHEMBL27705774 | 0.83 | MAOB (0.71) | ALDH1A1SMN1; SMN2APP | |
| SCHEMBL27705775 | 0.83 | MAOB (0.71) | ALDH1A1SMN1; SMN2APP | |
| SCHEMBL1745424 | 0.81 | MAOB (0.53) | SMN1; SMN2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1559422-B1 | RECEPTOR FUNCTION CONTROLLING AGENT | TAKEDA PHARMACEUTICAL (JP) | 2014-04-30 | — | — | EP | disclosed |
| US-20090012093-A1 | Receptor Function Regulator | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-01-08 | — | — | US | disclosed |
| EP-1559422-A1 | RECEPTOR FUNCTION CONTROLLING AGENT | Takeda Pharmaceutical Company Limited (JP) | 2005-08-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090012093-A1 | Receptor Function Regulator | GPR119, GIPR, INSR | ALDH1A1 4258/4885KDM4E 3200/4885PKM 4363/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.