Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 14/20 | 0.50 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27916947 | 0.83 | KIF11 (0.53) | KIF11KCNH2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL5282081 | 0.79 | KIF11 (0.48) | KIF11KCNH2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL11097246 | 0.79 | KIF11 (0.48) | KIF11CYP11B1CYP11B2KCNH2CYP3A4 | |
| SCHEMBL1149158 | 0.79 | KIF11 (0.64) | KIF11CYP11B1CYP11B2KCNH2CYP3A4 | |
| SCHEMBL5308454 | 0.76 | KCNN4 (0.47) | KIF11KCNH2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL3414508 | 0.75 | KIF11 (0.74) | KIF11KCNH2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL6555564 | 0.75 | KIF11 (0.54) | KIF11CYP11B1CYP11B2KCNH2CYP3A4 | |
| SCHEMBL5819108 | 0.74 | LMNA (0.45) | KIF11KCNH2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL5297663 | 0.74 | KIF11 (0.44) | KIF11KCNH2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL24371155 | 0.74 | CYP2C19 (0.45) | CYP3A4CYP2C9CYP2C19ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060216775-A1 | Compositions and methods for analysis and manipulation of enzymes in biosynthetic proteomes | THE REGENTS OF THE UNIVERSITY OF CALIFOENIA (US) | 2006-09-28 | — | — | US | disclosed |
| WO-2005003307-A2 | COMPOSITIONS AND METHODS FOR ANALYSIS AND MANIPULATION OF ENZYMES IN BIOSYNTHETIC PROTEOMES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2005-01-13 | — | — | WO | disclosed |
| WO-1991015242-A1 | CONJUGATE COMPOUNDS OF POLYMERS WITH OTHER ORGANIC MOLECULAR ENTITIES | SCHACHT ETIENNE HONORE (BE) | 1991-10-17 | — | — | WO | disclosed |