SCHEMBL6036029

SCHEMBL6036029

O=C(CCCCNCCc1ccccc1Cl)c1ccc2[nH]c(=O)[nH]c2c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 1/20 0.45
MAPT P10636 3/20 0.44
TP53 P04637 1/20 0.42
HIF1A Q16665 1/20 0.40
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
GAA P10253 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
CHRM2 P08172 1/20 0.39
GRIA1 P42261 2/20 0.39
CACNG8 Q8WXS5 2/20 0.39
KDM4E B2RXH2 1/20 0.38
LMNA P02545 1/20 0.38
CNR1 P21554 1/20 0.38
PLAAT3 P53816 1/20 0.38
PLAAT5 Q96KN8 1/20 0.38
PLAAT2 Q9NWW9 1/20 0.38
PLAAT4 Q9UL19 1/20 0.38
P2RX7 Q99572 1/20 0.38
ADRB2 P07550 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL4854024 0.99 GPR84 (0.44) GPR84MAPTTP53HIF1AMEN1
SCHEMBL6034791 0.85 POLB (0.45) MAPTCHRM2
SCHEMBL6035934 0.84 RAB9A (0.48) GPR84MAPTTP53L3MBTL1KDM4E
Hydrochloric Acid SCHEMBL4860176 0.84 POLB (0.44) MAPTMEN1KMT2ACHRM2
Hydrochloric Acid SCHEMBL4853949 0.84 RAB9A (0.48) GPR84MAPTTP53L3MBTL1KDM4E
SCHEMBL6035337 0.82 TP53 (0.47) MAPTTP53HIF1ALMNAP2RX7
SCHEMBL6035441 0.82 TP53 (0.44) MAPTTP53HIF1ALMNACNR1
Hydrochloric Acid SCHEMBL4855374 0.81 TP53 (0.46) MAPTTP53HIF1ALMNAP2RX7
Hydrochloric Acid SCHEMBL4861258 0.81 TP53 (0.44) MAPTTP53HIF1ALMNACNR1
SCHEMBL6034805 0.81 TAAR1 (0.39) GPR84MAPTTP53MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7132547-B2 Preventives/remedies for urinary disturbance TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2006-11-07 US claimed
US-20060063769-A1 Preventives/remedies for urinary disturbance TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2006-03-23 US claimed
US-7462628-B2 Preventives/remedies for urinary disturbance TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2008-12-09 US disclosed
US-7462628-B2 Preventives/remedies for urinary disturbance TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2008-12-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060063769-A1 Preventives/remedies for urinary disturbance ACHE, BPHL, CHRM1 GPR84 879/4885MAPT 1965/4885TP53 4560/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.