SCHEMBL6036381

SCHEMBL6036381

N=C1CCC(=N)C2=C1C(=O)NC2=O

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10618947 0.69 CRBN (0.37) CRBN
SCHEMBL710762 0.60
SCHEMBL6851025 0.60 GSK3B (0.44) CRBN
SCHEMBL11394866 0.58
SCHEMBL1649991 0.57 GSK3B (0.32)
SCHEMBL13665462 0.56 CRBN (0.47) CRBN
SCHEMBL171230 0.56 CRBN (0.40) CRBN
SCHEMBL996564 0.56 PTGS2 (0.33)
SCHEMBL845296 0.56
SCHEMBL2762093 0.55 ALDH1A1 (0.42) CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1721603-A1 Nanoparticles for bioconjugation Albert-Ludwigs-Universität Freiburg (DE) 2006-11-15 EP disclosed
US-20030201208-A1 Dynamic superparamagnetic markers KOCH, MARTIN (DK) 2003-10-30 US disclosed
WO-2001046461-A2 MODIFIED NUCLEIC ACIDS AND THEIR USE BIOCHIP TECHNOLOGIES GMBH (DE) 2001-06-28 WO disclosed
EP-1111069-A1 Modified nucleic acids and their use BioChip Technologies GmbH (DE) 2001-06-27 EP disclosed