Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.58 |
| ▸ | DRD2 | P14416 | 3/20 | 0.58 |
| ▸ | ABCB1 | P08183 | 6/20 | 0.50 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.47 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.47 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.47 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6006352 | 0.92 | HTR1A (0.46) | HTR1ADRD2ABCB1PTGER1PTGER4 | |
| SCHEMBL6745679 | 0.89 | PTGER1 (0.55) | HTR1ADRD2PTGER1PTGER4PTGER3 | |
| SCHEMBL29740762 | 0.86 | PTGS2 (0.60) | HTR1ADRD2ABCB1ALDH1A1HTT | |
| SCHEMBL868868 | 0.86 | PTGS2 (0.60) | HTR1ADRD2ABCB1ALDH1A1HTT | |
| SCHEMBL5478147 | 0.83 | HPGD (0.50) | DRD2TSHR | |
| SCHEMBL29733434 | 0.82 | HTR1A (0.50) | HTR1ADRD2ABCB1ALDH1A1HTT | |
| SCHEMBL15899172 | 0.82 | HTR1A (0.46) | HTR1ADRD2ABCB1PTGER1PTGER4 | |
| SCHEMBL29733421 | 0.82 | THRB (0.63) | HTR1ADRD2ABCB1PTGER1PTGER4 | |
| SCHEMBL606945 | 0.81 | NPSR1 (0.41) | HTR1ADRD2PTGER1PTGER4PTGER3 | |
| SCHEMBL608098 | 0.81 | NPSR1 (0.41) | HTR1ADRD2PTGER1PTGER4PTGER3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1185869-B1 | LIGAND-ANCHOR CONJUGATES FOR PRODUCING A BIOSENSOR LAYER | GRAFFINITY PHARMACEUTICALS AG (DE) | 2006-07-26 | — | — | EP | disclosed |