SCHEMBL6036847

SCHEMBL6036847

CC[Si](OC)(c1ccccc1)C(C)(C)Cl

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 1/20 0.31
TAAR1 Q96RJ0 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17319450 0.85 SLC6A2 (0.33) SLC6A2TAAR1
SCHEMBL6888150 0.84 SLC6A2 (0.31) SLC6A2TAAR1
SCHEMBL9456812 0.80 MAPK1 (0.36) SLC6A2TAAR1
SCHEMBL6036775 0.72 TP53 (0.32) SLC6A2TAAR1
SCHEMBL6036838 0.69 TP53 (0.30)
SCHEMBL534972 0.67 CA4 (0.35)
SCHEMBL705542 0.67 CA4 (0.35)
SCHEMBL296205 0.67 CA4 (0.35)
SCHEMBL9746360 0.66 TP53 (0.33) SLC6A2TAAR1
SCHEMBL837628 0.66 ESR1 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6991852-B2 A silica-based material that includes a silica-based substrate and a polymerized organic material disposed thereon. The polymerized organic material is made from reactive organic moieties bonded to the silica-based substrate. REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2006-01-31 US disclosed
US-20030219597-A1 Silica-based materials and methods REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2003-11-27 US disclosed
WO-2003078159-A1 SILICA-BASED MATERIALS AND METHODS REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2003-09-25 WO disclosed