Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9746360 | 0.84 | TP53 (0.33) | TP53TSHRTAAR1SLC6A2ESR1 | |
| SCHEMBL6036794 | 0.78 | RIPK1 (0.32) | — | |
| SCHEMBL6036838 | 0.75 | TP53 (0.30) | TP53TSHR | |
| SCHEMBL6036875 | 0.75 | KIF11 (0.31) | — | |
| SCHEMBL9745800 | 0.72 | NR1H2 (0.32) | TP53TAAR1SLC6A2 | |
| SCHEMBL6036847 | 0.72 | SLC6A2 (0.31) | TAAR1SLC6A2 | |
| SCHEMBL705504 | 0.72 | TP53 (0.38) | TP53TSHRESR1ESR2KCNN4 | |
| SCHEMBL703207 | 0.72 | TP53 (0.38) | TP53TSHRESR1ESR2KCNN4 | |
| SCHEMBL115193 | 0.72 | TP53 (0.38) | TP53TSHRESR1ESR2KCNN4 | |
| SCHEMBL6888150 | 0.71 | SLC6A2 (0.31) | TAAR1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6991852-B2 | A silica-based material that includes a silica-based substrate and a polymerized organic material disposed thereon. The polymerized organic material is made from reactive organic moieties bonded to the silica-based substrate. | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2006-01-31 | — | — | US | claimed |
| US-20030219597-A1 | Silica-based materials and methods | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2003-11-27 | — | — | US | claimed |
| WO-2003078159-A1 | SILICA-BASED MATERIALS AND METHODS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2003-09-25 | — | — | WO | claimed |
| US-6991852-B2 | A silica-based material that includes a silica-based substrate and a polymerized organic material disposed thereon. The polymerized organic material is made from reactive organic moieties bonded to the silica-based substrate. | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2006-01-31 | — | — | US | disclosed |
| US-20030219597-A1 | Silica-based materials and methods | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2003-11-27 | — | — | US | disclosed |
| WO-2003078159-A1 | SILICA-BASED MATERIALS AND METHODS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2003-09-25 | — | — | WO | disclosed |