Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6036794 | 0.85 | RIPK1 (0.32) | — | |
| SCHEMBL6036775 | 0.75 | TP53 (0.32) | — | |
| SCHEMBL9746360 | 0.72 | TP53 (0.33) | LMNA | |
| SCHEMBL9746349 | 0.71 | AOC3 (0.32) | LMNATRPA1 | |
| SCHEMBL2102454 | 0.67 | LMNA (0.35) | LMNATRPA1 | |
| SCHEMBL27513519 | 0.67 | TSHR (0.42) | KIF11LMNATRPA1 | |
| SCHEMBL1315271 | 0.67 | LMNA (0.35) | LMNATRPA1 | |
| SCHEMBL1313652 | 0.67 | LMNA (0.35) | LMNATRPA1 | |
| SCHEMBL1317173 | 0.66 | LMNA (0.34) | LMNATRPA1 | |
| SCHEMBL705504 | 0.65 | TP53 (0.38) | LMNATRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6991852-B2 | A silica-based material that includes a silica-based substrate and a polymerized organic material disposed thereon. The polymerized organic material is made from reactive organic moieties bonded to the silica-based substrate. | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2006-01-31 | — | — | US | disclosed |
| US-20030219597-A1 | Silica-based materials and methods | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2003-11-27 | — | — | US | disclosed |
| WO-2003078159-A1 | SILICA-BASED MATERIALS AND METHODS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2003-09-25 | — | — | WO | disclosed |