Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.50 |
| ▸ | RXRA | P19793 | 1/20 | 0.50 |
| ▸ | RXRB | P28702 | 1/20 | 0.50 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PDE5A | O76074 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.41 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6036878 | 1.00 | NR4A2 (0.50) | NR4A2RXRARXRBGRM2TP53 | |
| SCHEMBL6036919 | 1.00 | NR4A2 (0.50) | NR4A2RXRARXRBGRM2TP53 | |
| SCHEMBL6272276 | 0.94 | RXRA (0.61) | NR4A2RXRARXRBGRM2LMNA | |
| SCHEMBL6272688 | 0.91 | ALDH1A1 (0.48) | TP53LMNAALDH1A1GAATSHR | |
| SCHEMBL6267395 | 0.89 | ALDH1A1 (0.47) | GRM2TP53LMNAADORA2BALDH1A1 | |
| SCHEMBL6036872 | 0.89 | ALDH1A1 (0.47) | GRM2TP53LMNAADORA2BALDH1A1 | |
| SCHEMBL6269017 | 0.89 | ALDH1A1 (0.44) | TP53LMNAADORA2BALDH1A1GAA | |
| SCHEMBL6265402 | 0.88 | ALDH1A1 (0.43) | TP53LMNAADORA2BALDH1A1GAA | |
| SCHEMBL9031178 | 0.88 | ALDH1A1 (0.53) | GRM2TP53LMNAALDH1A1GAA | |
| SCHEMBL6269203 | 0.88 | ALDH1A1 (0.58) | TP53LMNAALDH1A1GAAPDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210137934-A1 | METHODS OF IDENTIFYING MYC-DRIVEN AND LIPOGENESIS-DEPENDENT NEOPLASMS AND METHODS OF TREATING THE SAME | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2021-05-13 | — | — | US | claimed |
| WO-2018170316-A1 | METHODS OF IDENTIFYING MYC-DRIVEN AND LIPOGENESIS-DEPENDENT NEOPLASMS AND METHODS OF TREATING THE SAME | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2018-09-20 | — | — | WO | claimed |
| EP-0916657-B9 | 1-phenylpyrrolidone derivatives having optical activity | TAIHO PHARMACEUTICAL CO LTD (JP) | 2006-05-17 | — | — | EP | claimed |
| EP-1000620-B1 | Lp(a)-LOWERING AGENTS AND APOPROTEIN (a) PRODUCTION INHIBITORS | TAIHO PHARMACEUTICAL CO LTD (JP) | 2005-12-07 | — | — | EP | claimed |
| EP-0916657-B1 | 1-phenylpyrrolidone derivatives having optical activity | TAIHO PHARMACEUTICAL CO LTD (JP) | 2005-11-09 | — | — | EP | claimed |
| US-6166036-A | Lp(a)-lowering agent and apolipoprotein (a) formation suppressing agent | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2000-12-26 | — | — | US | claimed |
| EP-1000620-A1 | Lp(a)-LOWERING AGENTS AND APOPROTEIN (a) PRODUCTION INHIBTORS | TAIHO PHARMACEUTICAL COMPANY, LIMITED (JP) | 2000-05-17 | — | — | EP | claimed |
| EP-0916657-A1 | 1-phenylpyrrolidone derivatives having optical activity | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1999-05-19 | — | — | EP | claimed |
| EP-0393607-B1 | Phenylcarboxylic acid derivatives having a hetero ring | OTSUKA PHARMA CO LTD (JP) | 1996-02-21 | — | — | EP | claimed |
| US-5475118-A | A chemical intermediates for making antilipemic agent | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1995-12-12 | — | — | US | claimed |
| US-20210137934-A1 | METHODS OF IDENTIFYING MYC-DRIVEN AND LIPOGENESIS-DEPENDENT NEOPLASMS AND METHODS OF TREATING THE SAME | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2021-05-13 | — | — | US | disclosed |
| EP-0916657-B9 | 1-phenylpyrrolidone derivatives having optical activity | TAIHO PHARMACEUTICAL CO LTD (JP) | 2006-05-17 | — | — | EP | disclosed |
| EP-1000620-B1 | Lp(a)-LOWERING AGENTS AND APOPROTEIN (a) PRODUCTION INHIBITORS | TAIHO PHARMACEUTICAL CO LTD (JP) | 2005-12-07 | — | — | EP | disclosed |
| EP-0916657-B1 | 1-phenylpyrrolidone derivatives having optical activity | TAIHO PHARMACEUTICAL CO LTD (JP) | 2005-11-09 | — | — | EP | disclosed |
| US-6166036-A | Lp(a)-lowering agent and apolipoprotein (a) formation suppressing agent | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2000-12-26 | — | — | US | disclosed |
| EP-0393607-B1 | Phenylcarboxylic acid derivatives having a hetero ring | OTSUKA PHARMA CO LTD (JP) | 1996-02-21 | — | — | EP | disclosed |
| US-5475118-A | A chemical intermediates for making antilipemic agent | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1995-12-12 | — | — | US | disclosed |
| EP-0627419-A1 | OPTICALLY ACTIVE 1-PHENYLPYRROLIDONE DERIVATIVE, INTERMEDIATE FOR PRODUCING THE SAME, AND PROCESS FOR PRODUCING BOTH | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1994-12-07 | — | — | EP | disclosed |
| US-5145865-A | Fatty acid, cholesterol synthesis inhibitors; enzyme inhibitors; antilipemic agents | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1992-09-08 | — | — | US | disclosed |
| EP-0393607-A2 | Phenylcarboxylic acid derivatives having a hetero ring | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1990-10-24 | — | — | EP | disclosed |