Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 4/20 | 0.61 |
| ▸ | RXRB | P28702 | 4/20 | 0.61 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 8/20 | 0.48 |
| ▸ | RAB9A | P51151 | 7/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.47 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.47 |
| ▸ | SLC6A5 | Q9Y345 | 3/20 | 0.46 |
| ▸ | RXRG | P48443 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6036878 | 0.94 | NR4A2 (0.50) | RXRARXRBNR4A2POLBKMT2A | |
| SCHEMBL6036919 | 0.94 | NR4A2 (0.50) | RXRARXRBNR4A2POLBKMT2A | |
| SCHEMBL6036880 | 0.94 | NR4A2 (0.50) | RXRARXRBNR4A2POLBKMT2A | |
| SCHEMBL6270269 | 0.91 | NR4A2 (0.48) | RXRARXRBNR4A2NPC1RAB9A | |
| SCHEMBL6267118 | 0.89 | NPC1 (0.59) | RXRARXRBNR4A2NPC1RAB9A | |
| SCHEMBL6267136 | 0.88 | NR4A1 (0.56) | NR4A2NPC1RAB9APOLBKMT2A | |
| SCHEMBL6269907 | 0.87 | RAB9A (0.63) | RXRARXRBNR4A2NPC1RAB9A | |
| SCHEMBL6270442 | 0.86 | RXRA (0.61) | RXRARXRBNR4A2NPC1RAB9A | |
| SCHEMBL6272688 | 0.85 | ALDH1A1 (0.48) | NPC1RAB9APOLBKMT2ALMNA | |
| SCHEMBL6270284 | 0.85 | RXRA (0.51) | RXRARXRBPOLBKMT2AGRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1000620-B1 | Lp(a)-LOWERING AGENTS AND APOPROTEIN (a) PRODUCTION INHIBITORS | TAIHO PHARMACEUTICAL CO LTD (JP) | 2005-12-07 | — | — | EP | disclosed |
| US-6166036-A | Lp(a)-lowering agent and apolipoprotein (a) formation suppressing agent | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2000-12-26 | — | — | US | disclosed |
| EP-1000620-A1 | Lp(a)-LOWERING AGENTS AND APOPROTEIN (a) PRODUCTION INHIBTORS | TAIHO PHARMACEUTICAL COMPANY, LIMITED (JP) | 2000-05-17 | — | — | EP | disclosed |
| EP-0393607-B1 | Phenylcarboxylic acid derivatives having a hetero ring | OTSUKA PHARMA CO LTD (JP) | 1996-02-21 | — | — | EP | disclosed |
| US-5145865-A | Fatty acid, cholesterol synthesis inhibitors; enzyme inhibitors; antilipemic agents | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1992-09-08 | — | — | US | disclosed |
| EP-0393607-A2 | Phenylcarboxylic acid derivatives having a hetero ring | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1990-10-24 | — | — | EP | disclosed |