Phosphoramidic Acid

Phosphoramidic Acid

SCHEMBL6036889

COC(C)N.NP(=O)(O)O

nearest known ligand 0.50

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LAP3 P28838 4/20 0.43
ANPEP P15144 5/20 0.39
ERAP1 Q9NZ08 1/20 0.39
ALDH1A1 P00352 2/20 0.36
FDPS P14324 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
MMP1 P03956 1/20 0.35
MMP2 P08253 1/20 0.35
MMP9 P14780 1/20 0.35
MMP8 P22894 1/20 0.35
CA9 Q16790 1/20 0.35
METAP1 P53582 1/20 0.34
SLC1A3 P43003 1/20 0.33
SLC1A2 P43004 1/20 0.33
SLC1A1 P43005 1/20 0.33
GABBR2 O75899 1/20 0.32
GABBR1 Q9UBS5 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphoric Acid SCHEMBL27732599 0.91 LAP3 (0.46) LAP3ANPEPERAP1ALDH1A1FDPS
Phosphoric Acid SCHEMBL27732607 0.91 LAP3 (0.46) LAP3ANPEPERAP1ALDH1A1FDPS
Phosphoric Acid SCHEMBL17746585 0.91 LAP3 (0.46) LAP3ANPEPERAP1ALDH1A1FDPS
Phosphoramidic Acid SCHEMBL4439626 0.81
SCHEMBL15982351 0.77
SCHEMBL19476 0.77
Bicarbonate SCHEMBL27732642 0.75
Bicarbonate SCHEMBL27732671 0.75 SLC1A3 (0.48) ALDH1A1CA1CA2CA9SLC1A3
Phosphoramidic Acid SCHEMBL220946 0.74 LAP3 (0.32) LAP3CA12CA1CA2MMP1
Iodide SCHEMBL19458794 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060246438-A1 Methods for the chemical and physical modification of nanotubes, methods for linking the nanotubes, methods for the directed positioning of nanotubes, and uses thereof COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2006-11-02 US disclosed
EP-1549662-A1 METHODS FOR THE CHEMICAL AND PHYSICAL MODIFICATION OF NANOTUBES, METHODS FOR LINKING THE NANOTUBES, METHODS FOR THE DIRECTED POSITIONING OF NANOTUBES, AND USES THEREOF COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2005-07-06 EP disclosed
US-6828148-B2 Compound for use in the treatment of infections, arthritis, artherosclerosis, restenosis, psoriasis, cancer and leukemia GENE SHEARS PTY. LIMITED (AU) 2004-12-07 US disclosed
WO-2004020450-A1 METHODS FOR THE CHEMICAL AND PHYSICAL MODIFICATION OF NANOTUBES, METHODS FOR LINKING THE NANOTUBES, METHODS FOR THE DIRECTED POSITIONING OF NANOTUBES, AND USES THEREOF COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2004-03-11 WO disclosed
EP-0837933-A4 OPTIMIZED MINIZYMES AND MINIRIBOZYMES AND USES THEREOF COMMW SCIENT IND RES ORG (AU) 2003-05-21 EP disclosed
US-20020155454-A1 Miniribozymes active at low magnesium ion concentrations GENE SHEARS PTY. LIMITED (AU) 2002-10-24 US disclosed
US-6277634-B1 HYBRIDIZED WITH TARGET RNA TO BE CLEAVED; MEDICAL DIAGNOSIS OR GENE THERAPY, DRUGS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANIZATION (AU) 2001-08-21 US disclosed
WO-2000039146-A1 MINIRIBOZYMES ACTIVE AT LOW MAGNESIUM ION CONCENTRATIONS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2000-07-06 WO disclosed
US-6001648-A NUCLEOTIDE SEQUENCE WHICH HYBRIDIZES TO AND CLEAVES TARGET RNA SEQUENCE; FOR DIAGNOSTIC OR THERAPEUTIC AGENTS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANIZATION (AU) 1999-12-14 US disclosed
EP-0837933-A1 OPTIMIZED MINIZYMES AND MINIRIBOZYMES AND USES THEREOF COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 1998-04-29 EP disclosed
WO-1996040906-A1 OPTIMIZED MINIZYMES AND MINIRIBOZYMES AND USES THEREOF COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 1996-12-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020155454-A1 Miniribozymes active at low magnesium ion concentrations EMG1, RNASE1, MMEL1 LAP3 568/4885ANPEP 674/4885ERAP1 406/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.